HCSGD entry for CMPK1
1. General information
| Official gene symbol | CMPK1 |
|---|---|
| Entrez ID | 51727 |
| Gene full name | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic |
| Other gene symbols | CK CMK CMPK UMK UMP-CMPK UMPK |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004127 | Cytidylate kinase activity | IEA | molecular_function |
| GO:0004550 | Nucleoside diphosphate kinase activity | IDA | molecular_function |
| GO:0004849 | Uridine kinase activity | TAS | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006139 | Nucleobase-containing compound metabolic process | IEA | biological_process |
| GO:0006165 | Nucleoside diphosphate phosphorylation | IDA | biological_process |
| GO:0006222 | UMP biosynthetic process | TAS | biological_process |
| GO:0006225 | UDP biosynthetic process | IEA | biological_process |
| GO:0006227 | DUDP biosynthetic process | IEA | biological_process |
| GO:0006240 | DCDP biosynthetic process | IEA | biological_process |
| GO:0009142 | Nucleoside triphosphate biosynthetic process | IDA | biological_process |
| GO:0009220 | Pyrimidine ribonucleotide biosynthetic process | TAS | biological_process |
| GO:0015949 | Nucleobase-containing small molecule interconversion | TAS | biological_process |
| GO:0018963 | Phthalate metabolic process | IEA | biological_process |
| GO:0019205 | Nucleobase-containing compound kinase activity | IEA | molecular_function |
| GO:0022602 | Ovulation cycle process | IEA | biological_process |
| GO:0033862 | UMP kinase activity | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046705 | CDP biosynthetic process | IEA | biological_process |
| GO:0055086 | Nucleobase-containing small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6952003533 | 0.4660033965 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0950705296 |
| GSE13712_SHEAR | Up | 0.0370170343 |
| GSE13712_STATIC | Up | 0.0932888637 |
| GSE19018 | Up | 0.1520713715 |
| GSE19899_A1 | Up | 0.2106704812 |
| GSE19899_A2 | Up | 0.1274947274 |
| PubMed_21979375_A1 | Up | 0.2855550103 |
| PubMed_21979375_A2 | Up | 0.0194698285 |
| GSE35957 | Up | 0.1797612229 |
| GSE36640 | Up | 0.2256090436 |
| GSE54402 | Up | 0.2059812519 |
| GSE9593 | Down | -0.0285094165 |
| GSE43922 | Down | -0.0127630086 |
| GSE24585 | Down | -0.0435288513 |
| GSE37065 | Down | -0.1186589316 |
| GSE28863_A1 | Down | -0.2754525184 |
| GSE28863_A2 | Up | 0.2109299743 |
| GSE28863_A3 | Down | -0.6118843873 |
| GSE28863_A4 | Down | -0.2285019073 |
| GSE48662 | Down | -0.2488981185 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Gemcitabine | DB00441 | APRD00201 |
| Cytidine-5'-Monophosphate | DB03403 | EXPT00796 |
| Uridine-5'-Diphosphate | DB03435 | EXPT03172 |
| P1-(Adenosine-5'-P5-(Uridine-5')Pentaphosphate | DB03664 | EXPT03194 |
| Tetrafluoroaluminate Ion | DB04444 | EXPT00497 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-374b-5p | MIMAT0004955 | MIRT016049 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-590-3p | MIMAT0004801 | MIRT016177 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024406 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025229 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT025611 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026115 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028815 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031434 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-484 | MIMAT0002174 | MIRT042359 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
