HCSGD entry for RAB8B
1. General information
| Official gene symbol | RAB8B |
|---|---|
| Entrez ID | 51762 |
| Gene full name | RAB8B, member RAS oncogene family |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003924 | GTPase activity | NAS | molecular_function |
| GO:0005102 | Receptor binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005778 | Peroxisomal membrane | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006184 | GTP catabolic process | NAS | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0008152 | Metabolic process | NAS | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0019003 | GDP binding | IDA | molecular_function |
| GO:0030670 | Phagocytic vesicle membrane | IEA | cellular_component |
| GO:0030911 | TPR domain binding | IEA | molecular_function |
| GO:0031346 | Positive regulation of cell projection organization | IEA | biological_process |
| GO:0034332 | Adherens junction organization | ISS | biological_process |
| GO:0045046 | Protein import into peroxisome membrane | IDA | biological_process |
| GO:0045335 | Phagocytic vesicle | IDA | cellular_component |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
| GO:0051286 | Cell tip | IEA | cellular_component |
| GO:0051461 | Positive regulation of corticotropin secretion | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0225599863 | 0.8740749440 | 0.3590567894 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0481695145 |
| GSE13712_SHEAR | Up | 0.1213370168 |
| GSE13712_STATIC | Up | 0.0906840169 |
| GSE19018 | Up | 0.3960214179 |
| GSE19899_A1 | Up | 0.6016078292 |
| GSE19899_A2 | Up | 0.4097920529 |
| PubMed_21979375_A1 | Up | 0.9690496714 |
| PubMed_21979375_A2 | Up | 0.5771514447 |
| GSE35957 | Up | 0.5687951413 |
| GSE36640 | Down | -0.9078412610 |
| GSE54402 | Down | -0.0837753160 |
| GSE9593 | Up | 0.7780560301 |
| GSE43922 | Up | 0.0822202993 |
| GSE24585 | Up | 0.2261496819 |
| GSE37065 | Up | 0.2275470536 |
| GSE28863_A1 | Up | 0.0788830437 |
| GSE28863_A2 | Up | 0.3530190904 |
| GSE28863_A3 | Down | -0.3065382981 |
| GSE28863_A4 | Up | 0.0987274941 |
| GSE48662 | Down | -0.7109404623 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Phosphoaminophosphonic Acid Guanylate Ester | DB02082 | EXPT01658 |
| Guanosine-5'-Diphosphate | DB04315 | EXPT01573 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-361-5p | MIMAT0000703 | MIRT020088 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT021910 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024415 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026284 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-101-3p | MIMAT0000099 | MIRT027257 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048745 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
