HCSGD entry for CFP
1. General information
| Official gene symbol | CFP |
|---|---|
| Entrez ID | 5199 |
| Gene full name | complement factor properdin |
| Other gene symbols | BFD PFC PFD PROPERDIN |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005615 | Extracellular space | TAS | cellular_component |
| GO:0006955 | Immune response | TAS | biological_process |
| GO:0006956 | Complement activation | TAS | biological_process |
| GO:0006957 | Complement activation, alternative pathway | TAS | biological_process |
| GO:0030449 | Regulation of complement activation | TAS | biological_process |
| GO:0031012 | Extracellular matrix | IDA | cellular_component |
| GO:0042742 | Defense response to bacterium | TAS | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3636627940 | 0.8479920292 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0522360125 |
| GSE13712_SHEAR | Up | 0.6238778985 |
| GSE13712_STATIC | Up | 0.2529244045 |
| GSE19018 | Down | -0.0410848433 |
| GSE19899_A1 | Down | -0.1201729172 |
| GSE19899_A2 | Up | 0.0191353837 |
| PubMed_21979375_A1 | Up | 0.2794935703 |
| PubMed_21979375_A2 | Up | 0.0507399593 |
| GSE35957 | Down | -0.1466423149 |
| GSE36640 | Up | 0.1007067651 |
| GSE54402 | Up | 0.1016508350 |
| GSE9593 | Up | 0.0214560842 |
| GSE43922 | Up | 0.1162328684 |
| GSE24585 | Up | 0.1024673655 |
| GSE37065 | Down | -0.0198142720 |
| GSE28863_A1 | Down | -0.0786831671 |
| GSE28863_A2 | Up | 0.0032393799 |
| GSE28863_A3 | Up | 0.3051432037 |
| GSE28863_A4 | Down | -0.0150331099 |
| GSE48662 | Down | -0.0022811794 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016885 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 3 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 23695235 | Using the PFC location identified from the structural analyses as a 'seed' region, it was further revealed that telomerase activity interacted with heroin use to impact age-sensitive brain functional networks (AlphaSim corrected P<0 |
| 23270390 | This study aimed to investigate the impact of early developmental stress and voluntary exercise on telomere length in the ventral hippocampus (VH) and prefrontal cortex (PFC) of the rat |
| 12511612 | Immunostaining of cyan fluorescent protein-labeled SRC-1 (CFP-SRC1)-expressing cells with antibody to promyelocytic leukemia (PML) protein showed significant overlap of the CFP fluorescence with the antibody stain |
| 12511612 | Cotransfection of cells with a plasmid expressing the CFP conjugate of Sp100 (another marker protein for the PML nuclear body) also showed colocalization of the yellow fluorescent protein (YFP)-SRC1 containing nuclear foci with the PML bodies in living cells |
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