HCSGD entry for LRP1B
1. General information
| Official gene symbol | LRP1B |
|---|---|
| Entrez ID | 53353 |
| Gene full name | low density lipoprotein receptor-related protein 1B |
| Other gene symbols | LRP-DIT LRPDIT |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005041 | Low-density lipoprotein receptor activity | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0006898 | Receptor-mediated endocytosis | TAS | biological_process |
| GO:0015031 | Protein transport | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0043235 | Receptor complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7822854717 | 0.5019969834 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2200663192 |
| GSE13712_SHEAR | Down | -0.1283429838 |
| GSE13712_STATIC | Up | 0.0821838540 |
| GSE19018 | Down | -0.1449066358 |
| GSE19899_A1 | Down | -0.1568602543 |
| GSE19899_A2 | Down | -0.0285469376 |
| PubMed_21979375_A1 | Down | -0.0594499110 |
| PubMed_21979375_A2 | Down | -0.3935846431 |
| GSE35957 | Up | 0.1765161624 |
| GSE36640 | Up | 0.3775814435 |
| GSE54402 | Up | 0.0698775328 |
| GSE9593 | Up | 0.0407734510 |
| GSE43922 | Up | 0.0079766372 |
| GSE24585 | Down | -0.2699572465 |
| GSE37065 | Down | -0.0320569630 |
| GSE28863_A1 | Up | 0.0288471978 |
| GSE28863_A2 | Up | 0.0681232986 |
| GSE28863_A3 | Up | 0.0936197441 |
| GSE28863_A4 | Up | 0.0026525569 |
| GSE48662 | Down | -0.0666343028 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016828 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028914 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
