HCSGD entry for ATP6V0A1
1. General information
| Official gene symbol | ATP6V0A1 |
|---|---|
| Entrez ID | 535 |
| Gene full name | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| Other gene symbols | ATP6N1 ATP6N1A Stv1 VPP1 Vph1 a1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000220 | Vacuolar proton-transporting V-type ATPase, V0 domain | IEA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006879 | Cellular iron ion homeostasis | TAS | biological_process |
| GO:0008286 | Insulin receptor signaling pathway | TAS | biological_process |
| GO:0010008 | Endosome membrane | TAS | cellular_component |
| GO:0015078 | Hydrogen ion transmembrane transporter activity | IEA | molecular_function |
| GO:0015991 | ATP hydrolysis coupled proton transport | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030670 | Phagocytic vesicle membrane | TAS | cellular_component |
| GO:0033179 | Proton-transporting V-type ATPase, V0 domain | IEA | cellular_component |
| GO:0033572 | Transferrin transport | TAS | biological_process |
| GO:0042470 | Melanosome | IEA | cellular_component |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0051117 | ATPase binding | IPI | molecular_function |
| GO:0051701 | Interaction with host | TAS | biological_process |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
| GO:0090382 | Phagosome maturation | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0011641427 | 0.9849561263 | 0.0914668657 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2959922523 |
| GSE13712_SHEAR | Down | -0.3324908989 |
| GSE13712_STATIC | Up | 0.6152390624 |
| GSE19018 | Up | 0.1171191770 |
| GSE19899_A1 | Up | 0.4823975414 |
| GSE19899_A2 | Up | 0.9036957114 |
| PubMed_21979375_A1 | Up | 1.8263358380 |
| PubMed_21979375_A2 | Up | 1.2618175553 |
| GSE35957 | Up | 0.7658397943 |
| GSE36640 | Up | 1.3886543376 |
| GSE54402 | Up | 0.4930085224 |
| GSE9593 | Up | 1.0563942374 |
| GSE43922 | Up | 0.7782647873 |
| GSE24585 | Up | 0.2123184603 |
| GSE37065 | Up | 0.1120778858 |
| GSE28863_A1 | Down | -0.1197978445 |
| GSE28863_A2 | Up | 0.8880299462 |
| GSE28863_A3 | Down | -0.4639556016 |
| GSE28863_A4 | Up | 0.0522406324 |
| GSE48662 | Up | 0.0199093658 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT001382 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT001651 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT017495 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
