HCSGD entry for ATP6AP1


1. General information

Official gene symbolATP6AP1
Entrez ID537
Gene full nameATPase, H+ transporting, lysosomal accessory protein 1
Other gene symbols16A ATP6IP1 ATP6S1 Ac45 CF2 VATPS1 XAP-3 XAP3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005215Transporter activityTASmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005774Vacuolar membraneIEAcellular_component
GO:0015991ATP hydrolysis coupled proton transportIEAbiological_process
GO:0015992Proton transportTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016469Proton-transporting two-sector ATPase complexTAScellular_component
GO:0033180Proton-transporting V-type ATPase, V1 domainIEAcellular_component
GO:0046933Proton-transporting ATP synthase activity, rotational mechanismIEAmolecular_function
GO:0046961Proton-transporting ATPase activity, rotational mechanismIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00555540820.98213763910.19653750001.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.6416905869
GSE13712_SHEARUp0.1931654863
GSE13712_STATICUp0.1054958313
GSE19018Up1.2980355863
GSE19899_A1Down-0.1516022847
GSE19899_A2Up0.8496729943
PubMed_21979375_A1Up0.4572517340
PubMed_21979375_A2Up0.4726992562
GSE35957Up0.0532109467
GSE36640Up1.3243045574
GSE54402Down-0.0205033570
GSE9593Up0.3665249703
GSE43922Up0.1737519980
GSE24585Up0.5276977447
GSE37065Up0.2567818062
GSE28863_A1Up0.2014069285
GSE28863_A2Up0.2462147490
GSE28863_A3Down-0.3694556312
GSE28863_A4Down-0.1370078620
GSE48662Up0.5701936635

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT030317MicroarrayFunctional MTI (Weak)19088304
hsa-miR-1226-5pMIMAT0005576MIRT036538CLASHFunctional MTI (Weak)23622248
hsa-miR-455-3pMIMAT0004784MIRT037865CLASHFunctional MTI (Weak)23622248
hsa-miR-15a-5pMIMAT0000068MIRT051337CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.