HCSGD entry for RIPK4
1. General information
| Official gene symbol | RIPK4 |
|---|---|
| Entrez ID | 54101 |
| Gene full name | receptor-interacting serine-threonine kinase 4 |
| Other gene symbols | ANKK2 ANKRD3 DIK NKRD3 PKK PPS2 RIP4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002009 | Morphogenesis of an epithelium | IMP | biological_process |
| GO:0004674 | Protein serine/threonine kinase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA ISS | cellular_component |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0051092 | Positive regulation of NF-kappaB transcription factor activity | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4996105505 | 0.7206343376 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0456652236 |
| GSE13712_SHEAR | Up | 0.1221116626 |
| GSE13712_STATIC | Up | 0.0525895857 |
| GSE19018 | Up | 0.2499850089 |
| GSE19899_A1 | Up | 0.1179451728 |
| GSE19899_A2 | Up | 0.0750682873 |
| PubMed_21979375_A1 | Up | 0.1667939055 |
| PubMed_21979375_A2 | Down | -0.1024136850 |
| GSE35957 | Down | -0.7278176614 |
| GSE36640 | Down | -0.0898711622 |
| GSE54402 | Up | 0.0565051335 |
| GSE9593 | Down | -0.0254310247 |
| GSE43922 | Up | 0.0228126552 |
| GSE24585 | Down | -0.0331951766 |
| GSE37065 | Up | 0.2214804805 |
| GSE28863_A1 | Down | -0.1098785836 |
| GSE28863_A2 | Up | 0.0160543805 |
| GSE28863_A3 | Up | 0.2365374098 |
| GSE28863_A4 | Up | 0.0575193736 |
| GSE48662 | Down | -0.1715496084 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022302 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029009 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
