HCSGD entry for TREM2
1. General information
| Official gene symbol | TREM2 |
|---|---|
| Entrez ID | 54209 |
| Gene full name | triggering receptor expressed on myeloid cells 2 |
| Other gene symbols | TREM-2 Trem2a Trem2b Trem2c |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001530 | Lipopolysaccharide binding | IEA | molecular_function |
| GO:0004872 | Receptor activity | TAS | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006959 | Humoral immune response | TAS | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0045087 | Innate immune response | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8005695718 | 0.7160254018 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0951323170 |
| GSE13712_SHEAR | Up | 0.0356706309 |
| GSE13712_STATIC | Down | -0.2340713320 |
| GSE19018 | Up | 0.1025930145 |
| GSE19899_A1 | Down | -0.0613128594 |
| GSE19899_A2 | Down | -0.1011831382 |
| PubMed_21979375_A1 | Up | 0.3164441343 |
| PubMed_21979375_A2 | Down | -0.1335348345 |
| GSE35957 | Down | -0.0212402876 |
| GSE36640 | Up | 0.1203964149 |
| GSE54402 | Down | -0.0136769968 |
| GSE9593 | Up | 0.0541684968 |
| GSE43922 | Up | 0.0132977262 |
| GSE24585 | Up | 0.0983842860 |
| GSE37065 | Up | 0.0761253060 |
| GSE28863_A1 | Up | 0.0460685378 |
| GSE28863_A2 | Up | 0.1003385162 |
| GSE28863_A3 | Down | -0.0083424740 |
| GSE28863_A4 | Down | -0.0490699416 |
| GSE48662 | Up | 0.1272094705 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
