HCSGD entry for POU1F1

1. General information

Official gene symbolPOU1F1
Entrez ID5449
Gene full namePOU class 1 homeobox 1
Other gene symbolsCPHD1 GHF-1 PIT1 POU1F1a Pit-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0001077RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcriptionIEAmolecular_function
GO:0001102RNA polymerase II activating transcription factor bindingIPImolecular_function
GO:0001105RNA polymerase II transcription coactivator activityIDAmolecular_function
GO:0001708Cell fate specificationIEAbiological_process
GO:0003682Chromatin bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIDA IEAmolecular_function
GO:0003714Transcription corepressor activityIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0008284Positive regulation of cell proliferationIEAbiological_process
GO:0008285Negative regulation of cell proliferationTASbiological_process
GO:0008340Determination of adult lifespanIEAbiological_process
GO:0030183B cell differentiationIEAbiological_process
GO:0032962Positive regulation of inositol trisphosphate biosynthetic processIEAbiological_process
GO:0040018Positive regulation of multicellular organism growthIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0043567Regulation of insulin-like growth factor receptor signaling pathwayIEAbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0051169Nuclear transportIEAbiological_process
GO:0060133Somatotropin secreting cell developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.45561292120.88801776530.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0232585766
GSE13712_SHEARUp0.0923459432
GSE13712_STATICUp0.0555858131
GSE19018Up0.1912307542
GSE19899_A1Up0.0620987459
GSE19899_A2Down-0.0565085849
PubMed_21979375_A1Up0.0303429172
PubMed_21979375_A2Down-0.1470847923
GSE35957Up0.1097133092
GSE36640Down-0.0469483990
GSE54402Up0.1778086478
GSE9593Down-0.0434460382
GSE43922Up0.0136340383
GSE24585Up0.1898334739
GSE37065Up0.0738464433
GSE28863_A1Up0.1294412117
GSE28863_A2Up0.1456673315
GSE28863_A3Up0.0630599558
GSE28863_A4Up0.0587104927
GSE48662Down-0.0262412691

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.