HCSGD entry for PPP1R1A
1. General information
| Official gene symbol | PPP1R1A |
|---|---|
| Entrez ID | 5502 |
| Gene full name | protein phosphatase 1, regulatory (inhibitor) subunit 1A |
| Other gene symbols | I1 IPP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004864 | Protein phosphatase inhibitor activity | IEA | molecular_function |
| GO:0004865 | Protein serine/threonine phosphatase inhibitor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005977 | Glycogen metabolic process | IEA | biological_process |
| GO:0007165 | Signal transduction | IEA | biological_process |
| GO:0043086 | Negative regulation of catalytic activity | TAS | biological_process |
| GO:0050790 | Regulation of catalytic activity | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5970814939 | 0.8347154971 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0023017281 |
| GSE13712_SHEAR | Up | 0.1253981157 |
| GSE13712_STATIC | Down | -0.0380107792 |
| GSE19018 | Up | 0.0122778627 |
| GSE19899_A1 | Up | 0.0380542897 |
| GSE19899_A2 | Up | 0.1171366104 |
| PubMed_21979375_A1 | Up | 0.1612051224 |
| PubMed_21979375_A2 | Up | 0.0750119610 |
| GSE35957 | Up | 0.2551912125 |
| GSE36640 | Up | 0.0269373784 |
| GSE54402 | Down | -0.0884574667 |
| GSE9593 | Down | -0.3199092253 |
| GSE43922 | Up | 0.1382020809 |
| GSE24585 | Down | -0.0356837534 |
| GSE37065 | Down | -0.0126998664 |
| GSE28863_A1 | Down | -0.0431124187 |
| GSE28863_A2 | Down | -0.1217222848 |
| GSE28863_A3 | Up | 0.0743610207 |
| GSE28863_A4 | Up | 0.1300402497 |
| GSE48662 | Up | 0.0665060702 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018310 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-296-3p | MIMAT0004679 | MIRT038385 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
