HCSGD entry for PDPR
1. General information
| Official gene symbol | PDPR |
|---|---|
| Entrez ID | 55066 |
| Gene full name | pyruvate dehydrogenase phosphatase regulatory subunit |
| Other gene symbols | PDP3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004047 | Aminomethyltransferase activity | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0006090 | Pyruvate metabolic process | TAS | biological_process |
| GO:0006546 | Glycine catabolic process | IEA | biological_process |
| GO:0010510 | Regulation of acetyl-CoA biosynthetic process from pyruvate | TAS | biological_process |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0044237 | Cellular metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4373438889 | 0.2263098666 | 0.9999902473 | 0.9145865193 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0470047102 |
| GSE13712_SHEAR | Down | -0.8273770018 |
| GSE13712_STATIC | Down | -0.7585294314 |
| GSE19018 | Up | 0.0377172437 |
| GSE19899_A1 | Down | -0.0484663335 |
| GSE19899_A2 | Up | 0.0360593155 |
| PubMed_21979375_A1 | Down | -0.3179195175 |
| PubMed_21979375_A2 | Up | 0.7828822705 |
| GSE35957 | Down | -0.0434192374 |
| GSE36640 | Down | -0.3816155003 |
| GSE54402 | Down | -0.0191061928 |
| GSE9593 | Down | -0.0982039768 |
| GSE43922 | Up | 0.0532131161 |
| GSE24585 | Up | 0.5733933787 |
| GSE37065 | Down | -0.1477226270 |
| GSE28863_A1 | Up | 0.2107022987 |
| GSE28863_A2 | Up | 0.1848032529 |
| GSE28863_A3 | Down | -0.3429455563 |
| GSE28863_A4 | Up | 0.0037740872 |
| GSE48662 | Up | 0.1134187054 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020998 | Proteomics | Functional MTI (Weak) | 20371610 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT023174 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT032052 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032497 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040806 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
