HCSGD entry for TRIM68
1. General information
| Official gene symbol | TRIM68 |
|---|---|
| Entrez ID | 55128 |
| Gene full name | tripartite motif containing 68 |
| Other gene symbols | GC109 RNF137 SS-56 SS56 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0035035 | Histone acetyltransferase binding | IPI | molecular_function |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
| GO:0050681 | Androgen receptor binding | IPI | molecular_function |
| GO:0051865 | Protein autoubiquitination | IDA | biological_process |
| GO:0060765 | Regulation of androgen receptor signaling pathway | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8920711371 | 0.0298770677 | 0.9999902473 | 0.3266372354 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0212343430 |
| GSE13712_SHEAR | Down | -0.5268913016 |
| GSE13712_STATIC | Down | -0.0940868573 |
| GSE19018 | Down | -0.1821100217 |
| GSE19899_A1 | Down | -0.6380727568 |
| GSE19899_A2 | Down | -0.9522793184 |
| PubMed_21979375_A1 | Down | -1.0747639052 |
| PubMed_21979375_A2 | Down | -0.0549234126 |
| GSE35957 | Down | -0.7798542354 |
| GSE36640 | Down | -0.0796745302 |
| GSE54402 | Down | -0.5989204736 |
| GSE9593 | Down | -0.0534204592 |
| GSE43922 | Down | -0.3559744145 |
| GSE24585 | Up | 0.4285610473 |
| GSE37065 | Up | 0.0594634032 |
| GSE28863_A1 | Up | 0.4709829037 |
| GSE28863_A2 | Up | 0.3341826522 |
| GSE28863_A3 | Down | -0.3488079418 |
| GSE28863_A4 | Down | -0.0553505312 |
| GSE48662 | Up | 0.0647990693 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024356 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026905 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030315 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
