HCSGD entry for ERBB2IP
1. General information
| Official gene symbol | ERBB2IP |
|---|---|
| Entrez ID | 55914 |
| Gene full name | erbb2 interacting protein |
| Other gene symbols | ERBIN LAP2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005176 | ErbB-2 class receptor binding | TAS | molecular_function |
| GO:0005178 | Integrin binding | IPI | molecular_function |
| GO:0005200 | Structural constituent of cytoskeleton | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005604 | Basement membrane | TAS | cellular_component |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA TAS | cellular_component |
| GO:0006605 | Protein targeting | IEA | biological_process |
| GO:0007049 | Cell cycle | NAS | biological_process |
| GO:0007155 | Cell adhesion | NAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007173 | Epidermal growth factor receptor signaling pathway | TAS | biological_process |
| GO:0007229 | Integrin-mediated signaling pathway | NAS | biological_process |
| GO:0009925 | Basal plasma membrane | NAS | cellular_component |
| GO:0016049 | Cell growth | NAS | biological_process |
| GO:0030056 | Hemidesmosome | IDA | cellular_component |
| GO:0031965 | Nuclear membrane | IEA | cellular_component |
| GO:0045104 | Intermediate filament cytoskeleton organization | NAS | biological_process |
| GO:0045175 | Basal protein localization | NAS | biological_process |
| GO:0045197 | Establishment or maintenance of epithelial cell apical/basal polarity | NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9862902017 | 0.0084815698 | 0.9999902473 | 0.1841600989 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4894465554 |
| GSE13712_SHEAR | Down | -0.0500195873 |
| GSE13712_STATIC | Down | -0.1346201994 |
| GSE19018 | Up | 0.0892219009 |
| GSE19899_A1 | Down | -0.3170580704 |
| GSE19899_A2 | Down | -0.5620200761 |
| PubMed_21979375_A1 | Down | -0.4405041204 |
| PubMed_21979375_A2 | Down | -0.4118622784 |
| GSE35957 | Up | 0.0192901077 |
| GSE36640 | Down | -0.4574094536 |
| GSE54402 | Down | -0.0893424972 |
| GSE9593 | Down | -0.0838347016 |
| GSE43922 | Down | -0.4450019288 |
| GSE24585 | Up | 0.4081557931 |
| GSE37065 | Up | 0.0161259760 |
| GSE28863_A1 | Down | -0.1389921570 |
| GSE28863_A2 | Down | -0.2491214118 |
| GSE28863_A3 | Down | -0.7342074347 |
| GSE28863_A4 | Down | -0.5739117891 |
| GSE48662 | Down | -0.4434349792 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-429 | MIMAT0001536 | MIRT016636 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-200a-3p | MIMAT0000682 | MIRT020347 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT021046 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-200c-3p | MIMAT0000617 | MIRT021069 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-141-3p | MIMAT0000432 | MIRT021659 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-200b-3p | MIMAT0000318 | MIRT024125 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-33a-5p | MIMAT0000091 | MIRT028201 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-32-5p | MIMAT0000090 | MIRT028336 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030329 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037027 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-141-3p | MIMAT0000432 | NA | hsa-miR-141 | 20005803 | |||
| hsa-miR-200a-3p | MIMAT0000682 | NA | hsa-miR-200a | 20005803 | |||
| hsa-miR-200b-3p | MIMAT0000318 | NA | hsa-miR-200b | 20005803 | |||
| hsa-miR-429 | MIMAT0001536 | NA | hsa-miR-429 | 20005803 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
