HCSGD entry for KLHL7
1. General information
| Official gene symbol | KLHL7 |
|---|---|
| Entrez ID | 55975 |
| Gene full name | kelch-like family member 7 |
| Other gene symbols | KLHL6 SBBI26 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0016567 | Protein ubiquitination | IDA IEA | biological_process |
| GO:0031463 | Cul3-RING ubiquitin ligase complex | IDA | cellular_component |
| GO:0042803 | Protein homodimerization activity | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2061996695 | 0.2835215341 | 0.8752429447 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0472056230 |
| GSE13712_SHEAR | Up | 0.0210419016 |
| GSE13712_STATIC | Up | 0.0265201545 |
| GSE19018 | Down | -0.1894942089 |
| GSE19899_A1 | Up | 0.2615655099 |
| GSE19899_A2 | Up | 0.3006294233 |
| PubMed_21979375_A1 | Up | 0.8399432553 |
| PubMed_21979375_A2 | Up | 0.1328297078 |
| GSE35957 | Down | -0.7570129348 |
| GSE36640 | Down | -0.4836307450 |
| GSE54402 | Up | 0.4779859502 |
| GSE9593 | Down | -0.2284109503 |
| GSE43922 | Up | 0.0529750713 |
| GSE24585 | Up | 0.3119945862 |
| GSE37065 | Up | 0.1710554165 |
| GSE28863_A1 | Up | 0.1950791439 |
| GSE28863_A2 | Up | 0.2608690322 |
| GSE28863_A3 | Down | -0.3707229321 |
| GSE28863_A4 | Down | -0.2957251269 |
| GSE48662 | Down | -0.5425127104 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019844 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-181b-5p | MIMAT0000257 | MIRT047233 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT048153 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
