HCSGD entry for BDH2
1. General information
| Official gene symbol | BDH2 |
|---|---|
| Entrez ID | 56898 |
| Gene full name | 3-hydroxybutyrate dehydrogenase, type 2 |
| Other gene symbols | DHRS6 EFA6R PRO20933 SDR15C1 UCPA-OR UNQ6308 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003858 | 3-hydroxybutyrate dehydrogenase activity | IDA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0006635 | Fatty acid beta-oxidation | IDA | biological_process |
| GO:0008667 | 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity | IEA | molecular_function |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0016628 | Oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor | IEA ISS | molecular_function |
| GO:0019290 | Siderophore biosynthetic process | IEA ISS | biological_process |
| GO:0042168 | Heme metabolic process | ISS | biological_process |
| GO:0051287 | NAD binding | IDA | molecular_function |
| GO:0055072 | Iron ion homeostasis | IEA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5014131986 | 0.0270832301 | 0.9999902473 | 0.3140633480 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5699200914 |
| GSE13712_SHEAR | Down | -0.4640927238 |
| GSE13712_STATIC | Down | -0.2235482933 |
| GSE19018 | Down | -0.4747883502 |
| GSE19899_A1 | Down | -0.5819712468 |
| GSE19899_A2 | Down | -0.9143917577 |
| PubMed_21979375_A1 | Down | -0.9388732282 |
| PubMed_21979375_A2 | Down | -0.3777546437 |
| GSE35957 | Up | 0.1393554946 |
| GSE36640 | Up | 1.0917608186 |
| GSE54402 | Down | -0.4032958698 |
| GSE9593 | Up | 0.1182766366 |
| GSE43922 | Down | -0.3136018951 |
| GSE24585 | Up | 0.5692070683 |
| GSE37065 | Up | 0.4432383482 |
| GSE28863_A1 | Up | 0.2280137555 |
| GSE28863_A2 | Down | -0.0382946896 |
| GSE28863_A3 | Down | -0.5986840283 |
| GSE28863_A4 | Down | -0.1586685633 |
| GSE48662 | Down | -0.0793931594 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-346 | MIMAT0000773 | MIRT004219 | Microarray | Functional MTI (Weak) | 16822819 |
| hsa-miR-375 | MIMAT0000728 | MIRT019992 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT031043 | Microarray | Functional MTI (Weak) | 20048743 |
| hsa-miR-766-3p | MIMAT0003888 | MIRT039022 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
