HCSGD entry for MEIS3
1. General information
| Official gene symbol | MEIS3 |
|---|---|
| Entrez ID | 56917 |
| Gene full name | Meis homeobox 3 |
| Other gene symbols | MRG2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001077 | RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription | IEA | molecular_function |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0043565 | Sequence-specific DNA binding | IDA IEA | molecular_function |
| GO:0051897 | Positive regulation of protein kinase B signaling | IEA | biological_process |
| GO:2001234 | Negative regulation of apoptotic signaling pathway | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4389566696 | 0.1118585844 | 0.9999902473 | 0.6407430374 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1847819370 |
| GSE13712_SHEAR | Up | 0.0206165797 |
| GSE13712_STATIC | Down | -0.0098152293 |
| GSE19018 | Up | 0.1197781974 |
| GSE19899_A1 | Down | -0.0414368818 |
| GSE19899_A2 | Up | 0.3355810549 |
| PubMed_21979375_A1 | Up | 0.6746594227 |
| PubMed_21979375_A2 | Up | 0.1838005711 |
| GSE35957 | Up | 0.0013877264 |
| GSE36640 | Up | 0.1289157042 |
| GSE54402 | Up | 0.0803271575 |
| GSE9593 | Up | 0.0015152717 |
| GSE43922 | Up | 0.0568586289 |
| GSE24585 | Down | -0.1830350970 |
| GSE37065 | Up | 0.0024369143 |
| GSE28863_A1 | Up | 0.1331900369 |
| GSE28863_A2 | Down | -0.5503987665 |
| GSE28863_A3 | Down | -1.1818298504 |
| GSE28863_A4 | Down | -0.5351498049 |
| GSE48662 | Up | 0.2241823109 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT016926 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-130b-5p | MIMAT0004680 | MIRT038310 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
