HCSGD entry for OTUD7B
1. General information
| Official gene symbol | OTUD7B |
|---|---|
| Entrez ID | 56957 |
| Gene full name | OTU domain containing 7B |
| Other gene symbols | CEZANNE ZA20D1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002385 | Mucosal immune response | IEA ISS | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0004221 | Ubiquitin thiolesterase activity | IEA ISS | molecular_function |
| GO:0004843 | Ubiquitin-specific protease activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0008234 | Cysteine-type peptidase activity | IEA ISS | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0015630 | Microtubule cytoskeleton | IDA | cellular_component |
| GO:0035871 | Protein K11-linked deubiquitination | IDA | biological_process |
| GO:0043124 | Negative regulation of I-kappaB kinase/NF-kappaB signaling | IDA | biological_process |
| GO:0070530 | K63-linked polyubiquitin binding | IEA | molecular_function |
| GO:0070536 | Protein K63-linked deubiquitination | IDA | biological_process |
| GO:0071108 | Protein K48-linked deubiquitination | IEA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0899672543 | 0.8744228829 | 0.6303860793 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0394706672 |
| GSE13712_SHEAR | Up | 0.3516867131 |
| GSE13712_STATIC | Up | 0.1919383804 |
| GSE19018 | Down | -0.2116945203 |
| GSE19899_A1 | Up | 0.0576014477 |
| GSE19899_A2 | Up | 0.1652804196 |
| PubMed_21979375_A1 | Up | 0.0063959413 |
| PubMed_21979375_A2 | Up | 0.0625146921 |
| GSE35957 | Down | -0.1850386284 |
| GSE36640 | Up | 0.1597044939 |
| GSE54402 | Up | 0.4076764815 |
| GSE9593 | Down | -0.0178549013 |
| GSE43922 | Up | 0.3174215535 |
| GSE24585 | Up | 0.1477979229 |
| GSE37065 | Down | -0.0723414351 |
| GSE28863_A1 | Up | 0.7982932011 |
| GSE28863_A2 | Up | 0.4683885210 |
| GSE28863_A3 | Down | -0.2562005002 |
| GSE28863_A4 | Down | -0.3645508539 |
| GSE48662 | Up | 0.4933949991 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1229-3p | MIMAT0005584 | MIRT036370 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-877-5p | MIMAT0004949 | MIRT037334 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-339-5p | MIMAT0000764 | MIRT042784 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051066 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
