HCSGD entry for PRDM8


1. General information

Official gene symbolPRDM8
Entrez ID56978
Gene full namePR domain containing 8
Other gene symbolsPFM5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingIEAmolecular_function
GO:0003682Chromatin bindingIEAmolecular_function
GO:0003714Transcription corepressor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0021540Corpus callosum morphogenesisIEAbiological_process
GO:0021957Corticospinal tract morphogenesisIEAbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0046974Histone methyltransferase activity (H3-K9 specific)IEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.78090126510.40036927930.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0506566807
GSE13712_SHEARUp0.0392946192
GSE13712_STATICUp0.1099000598
GSE19018Up0.2727533345
GSE19899_A1Down-0.0545343105
GSE19899_A2Up0.0652635556
PubMed_21979375_A1Down-0.6303938780
PubMed_21979375_A2Down-0.1809556106
GSE35957Down-0.0604594915
GSE36640Down-0.8696952108
GSE54402Down-0.0806889951
GSE9593Up0.0380613696
GSE43922Down-0.0591363992
GSE24585Up0.1704951688
GSE37065Up0.4076355665
GSE28863_A1Up0.1452731120
GSE28863_A2Up0.1798857225
GSE28863_A3Down-0.0455912251
GSE28863_A4Up0.0433329709
GSE48662Down-0.2915314328

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-7-5pMIMAT0000252MIRT025734MicroarrayFunctional MTI (Weak)17612493
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.