HCSGD entry for SLURP1
1. General information
| Official gene symbol | SLURP1 |
|---|---|
| Entrez ID | 57152 |
| Gene full name | secreted LY6/PLAUR domain containing 1 |
| Other gene symbols | ANUP ARS ArsB LY6LS MDM |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001775 | Cell activation | NAS | biological_process |
| GO:0005125 | Cytokine activity | NAS | molecular_function |
| GO:0005576 | Extracellular region | NAS | cellular_component |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0007155 | Cell adhesion | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4491870104 | 0.8351100566 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0215827913 |
| GSE13712_SHEAR | Down | -0.2822019036 |
| GSE13712_STATIC | Up | 0.2419374449 |
| GSE19018 | Up | 0.1514051886 |
| GSE19899_A1 | Up | 0.0920974020 |
| GSE19899_A2 | Up | 0.0148383778 |
| PubMed_21979375_A1 | Up | 0.0047745369 |
| PubMed_21979375_A2 | Down | -0.0006902059 |
| GSE35957 | Up | 0.0004553355 |
| GSE36640 | Up | 0.1409015700 |
| GSE54402 | Down | -0.0057375008 |
| GSE9593 | Down | -0.0160304116 |
| GSE43922 | Up | 0.0498525962 |
| GSE24585 | Up | 0.0976525283 |
| GSE37065 | Down | -0.0464461972 |
| GSE28863_A1 | Down | -0.0599579142 |
| GSE28863_A2 | Up | 0.1210156259 |
| GSE28863_A3 | Up | 0.2382607325 |
| GSE28863_A4 | Up | 0.0529596433 |
| GSE48662 | Up | 0.0283918858 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 23262034 | Given that Mdm2 and Mdm4 inhibit p53 activities to promote tumor development, small molecules and peptides were developed to abrogate the inhibition of p53 by Mdm proteins |
| 19855165 | We discuss that Mdm antagonists could be used in combination with chemotherapy to reversibly arrest normal cells, thus protecting them during chemotherapy of cancer (cyclotherapy) |
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