HCSGD entry for ARRDC3
1. General information
| Official gene symbol | ARRDC3 |
|---|---|
| Entrez ID | 57561 |
| Gene full name | arrestin domain containing 3 |
| Other gene symbols | TLIMP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001659 | Temperature homeostasis | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005768 | Endosome | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0031651 | Negative regulation of heat generation | IEA | biological_process |
| GO:0031699 | Beta-3 adrenergic receptor binding | IDA | molecular_function |
| GO:0044252 | Negative regulation of multicellular organismal metabolic process | IEA | biological_process |
| GO:0051443 | Positive regulation of ubiquitin-protein ligase activity | IPI | biological_process |
| GO:0060613 | Fat pad development | IEA | biological_process |
| GO:0071879 | Positive regulation of adrenergic receptor signaling pathway | IEA | biological_process |
| GO:0090327 | Negative regulation of locomotion involved in locomotory behavior | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3275140002 | 0.0021850880 | 0.9999902473 | 0.0900057903 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 1.2393530095 |
| GSE13712_SHEAR | Down | -0.2907508434 |
| GSE13712_STATIC | Down | -0.6192603484 |
| GSE19018 | Up | 0.3780719736 |
| GSE19899_A1 | Down | -1.1597165241 |
| GSE19899_A2 | Down | -1.6811697667 |
| PubMed_21979375_A1 | Down | -1.7984202319 |
| PubMed_21979375_A2 | Down | -0.6071797775 |
| GSE35957 | Down | -0.1030932270 |
| GSE36640 | Up | 0.4765198440 |
| GSE54402 | Down | -0.9635001369 |
| GSE9593 | Down | -1.2364847548 |
| GSE43922 | Down | -0.9351608831 |
| GSE24585 | Up | 1.1439844547 |
| GSE37065 | Up | 0.3952482779 |
| GSE28863_A1 | Up | 0.0165003741 |
| GSE28863_A2 | Up | 0.5490224148 |
| GSE28863_A3 | Down | -0.6158344631 |
| GSE28863_A4 | Down | -0.3753348941 |
| GSE48662 | Down | -0.5228651503 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017348 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020215 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-148a-3p | MIMAT0000243 | MIRT026009 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031205 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052564 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
