HCSGD entry for ARHGAP21
1. General information
| Official gene symbol | ARHGAP21 |
|---|---|
| Entrez ID | 57584 |
| Gene full name | Rho GTPase activating protein 21 |
| Other gene symbols | ARHGAP10 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0005096 | GTPase activator activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IDA | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0007030 | Golgi organization | IMP | biological_process |
| GO:0007165 | Signal transduction | IEA | biological_process |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0030659 | Cytoplasmic vesicle membrane | IEA | cellular_component |
| GO:0051683 | Establishment of Golgi localization | IDA | biological_process |
| GO:0051684 | Maintenance of Golgi location | IMP | biological_process |
| GO:0072384 | Organelle transport along microtubule | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3735057521 | 0.7432247369 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2310134245 |
| GSE13712_SHEAR | Up | 0.3568895870 |
| GSE13712_STATIC | Up | 0.0891323469 |
| GSE19018 | Up | 0.2357949221 |
| GSE19899_A1 | Down | -0.0602161138 |
| GSE19899_A2 | Up | 0.1590590464 |
| PubMed_21979375_A1 | Down | -0.0185536162 |
| PubMed_21979375_A2 | Up | 0.2751949188 |
| GSE35957 | Up | 0.0456293956 |
| GSE36640 | Down | -0.0554165401 |
| GSE54402 | Down | -0.0075752883 |
| GSE9593 | Down | -0.0968756729 |
| GSE43922 | Down | -0.0675404381 |
| GSE24585 | Down | -0.2321607757 |
| GSE37065 | Up | 0.1445479423 |
| GSE28863_A1 | Up | 0.1838751800 |
| GSE28863_A2 | Up | 0.1087829863 |
| GSE28863_A3 | Up | 0.0330567425 |
| GSE28863_A4 | Up | 0.1041249927 |
| GSE48662 | Down | -0.2745256004 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017485 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030816 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-361-3p | MIMAT0004682 | MIRT038266 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-183-5p | MIMAT0000261 | MIRT047126 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
