HCSGD entry for HES4
1. General information
| Official gene symbol | HES4 |
|---|---|
| Entrez ID | 57801 |
| Gene full name | hairy and enhancer of split 4 (Drosophila) |
| Other gene symbols | bHLHb42 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0007399 | Nervous system development | IEA | biological_process |
| GO:0008134 | Transcription factor binding | NAS | molecular_function |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0046983 | Protein dimerization activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0446407773 | 0.3120012272 | 0.4696202638 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.6135646117 |
| GSE13712_SHEAR | Up | 0.4661489463 |
| GSE13712_STATIC | Up | 0.9979620124 |
| GSE19018 | Down | -0.1289599385 |
| GSE19899_A1 | Down | -0.4470798902 |
| GSE19899_A2 | Up | 0.4857951444 |
| PubMed_21979375_A1 | Down | -0.5900725714 |
| PubMed_21979375_A2 | Up | 0.5856163249 |
| GSE35957 | Down | -0.7248764123 |
| GSE36640 | Down | -0.0786635130 |
| GSE54402 | Up | 0.2036403765 |
| GSE9593 | Up | 0.0278505296 |
| GSE43922 | Up | 0.0798253167 |
| GSE24585 | Up | 0.0015978394 |
| GSE37065 | Up | 0.0042837381 |
| GSE28863_A1 | Up | 0.0730059891 |
| GSE28863_A2 | Up | 0.3266696206 |
| GSE28863_A3 | Up | 0.8991943517 |
| GSE28863_A4 | Up | 0.0979000752 |
| GSE48662 | Up | 0.8103176902 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-423-5p | MIMAT0004748 | MIRT038130 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045541 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
