HCSGD entry for RASGRF2

1. General information

Official gene symbolRASGRF2
Entrez ID5924
Gene full nameRas protein-specific guanine nucleotide-releasing factor 2
Other gene symbolsGRF2 RAS-GRF2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005089Rho guanyl-nucleotide exchange factor activityIEAmolecular_function
GO:0005516Calmodulin bindingIEAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005789Endoplasmic reticulum membraneIEAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0007264Small GTPase mediated signal transductionIEA TASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0043065Positive regulation of apoptotic processTASbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0051056Regulation of small GTPase mediated signal transductionTASbiological_process
GO:0097190Apoptotic signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00757668020.71037153980.22701568181.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3301199162
GSE13712_SHEARUp0.4176792702
GSE13712_STATICUp0.6965360545
GSE19018Down-0.6285403484
GSE19899_A1Up0.0560364271
GSE19899_A2Up1.0478104260
PubMed_21979375_A1Up0.9678040397
PubMed_21979375_A2Up1.8333210412
GSE35957Up0.1841387730
GSE36640Up0.7452585562
GSE54402Up1.0520591301
GSE9593Up0.0147116103
GSE43922Up0.3061118918
GSE24585Down-0.5017799438
GSE37065Up0.0020494884
GSE28863_A1Up0.1779016554
GSE28863_A2Up0.2332021425
GSE28863_A3Down-0.2623001506
GSE28863_A4Down-0.1064171786
GSE48662Up0.0664447242

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.