HCSGD entry for PLEKHA2
1. General information
| Official gene symbol | PLEKHA2 |
|---|---|
| Entrez ID | 59339 |
| Gene full name | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 |
| Other gene symbols | TAPP2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001954 | Positive regulation of cell-matrix adhesion | IMP | biological_process |
| GO:0001968 | Fibronectin binding | IMP | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005545 | 1-phosphatidylinositol binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0016020 | Membrane | IDA | cellular_component |
| GO:0030165 | PDZ domain binding | IEA | molecular_function |
| GO:0043234 | Protein complex | IDA | cellular_component |
| GO:0043236 | Laminin binding | IMP | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9792400973 | 0.0002187455 | 0.9999902473 | 0.0258772321 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.9791694848 |
| GSE13712_SHEAR | Up | 0.1841344363 |
| GSE13712_STATIC | Up | 0.1851065520 |
| GSE19018 | Up | 0.9713156977 |
| GSE19899_A1 | Down | -0.6963220812 |
| GSE19899_A2 | Down | -1.3908171609 |
| PubMed_21979375_A1 | Down | -1.9335613629 |
| PubMed_21979375_A2 | Down | -0.6002203774 |
| GSE35957 | Down | -0.6971966007 |
| GSE36640 | Down | -1.6235578962 |
| GSE54402 | Down | -0.9615957991 |
| GSE9593 | Down | -0.1489318530 |
| GSE43922 | Down | -0.8526182115 |
| GSE24585 | Down | -0.0154689768 |
| GSE37065 | Down | -0.3365741382 |
| GSE28863_A1 | Down | -1.0203029638 |
| GSE28863_A2 | Down | -0.7090235820 |
| GSE28863_A3 | Down | -1.3322346196 |
| GSE28863_A4 | Down | -0.2361048862 |
| GSE48662 | Down | -0.1115762088 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
