HCSGD entry for PPCDC


1. General information

Official gene symbolPPCDC
Entrez ID60490
Gene full namephosphopantothenoylcysteine decarboxylase
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003824Catalytic activityIEAmolecular_function
GO:0004633Phosphopantothenoylcysteine decarboxylase activityIDA TASmolecular_function
GO:0005829CytosolTAScellular_component
GO:0006766Vitamin metabolic processTASbiological_process
GO:0006767Water-soluble vitamin metabolic processTASbiological_process
GO:0009108Coenzyme biosynthetic processTASbiological_process
GO:0015937Coenzyme A biosynthetic processIDA IEAbiological_process
GO:0015939Pantothenate metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.11634383570.61210636750.70016902371.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0796151621
GSE13712_SHEARUp0.0647235973
GSE13712_STATICUp0.0781294269
GSE19018Up0.1249656947
GSE19899_A1Up0.0025943214
GSE19899_A2Up0.7051381652
PubMed_21979375_A1Up2.4174557199
PubMed_21979375_A2Up0.1444950985
GSE35957Down-0.4299922871
GSE36640Up0.2979164879
GSE54402Up0.4062845790
GSE9593Down-0.4024277457
GSE43922Up0.0638817889
GSE24585Down-0.3925867162
GSE37065Up0.0614119463
GSE28863_A1Down-0.0098694577
GSE28863_A2Down-0.1474034519
GSE28863_A3Up0.0269108973
GSE28863_A4Up0.0195954997
GSE48662Up0.0639596546

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Riboflavin MonophosphateDB03247 EXPT01458
PantothenoylaminoethenethiolDB03738 EXPT02522

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.