HCSGD entry for LHPP
1. General information
| Official gene symbol | LHPP |
|---|---|
| Entrez ID | 64077 |
| Gene full name | phospholysine phosphohistidine inorganic pyrophosphate phosphatase |
| Other gene symbols | HDHD2B |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000287 | Magnesium ion binding | ISS | molecular_function |
| GO:0004427 | Inorganic diphosphatase activity | IDA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0006470 | Protein dephosphorylation | ISS | biological_process |
| GO:0006796 | Phosphate-containing compound metabolic process | IDA | biological_process |
| GO:0008969 | Phosphohistidine phosphatase activity | ISS | molecular_function |
| GO:0042803 | Protein homodimerization activity | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8782603473 | 0.1420359941 | 0.9999902473 | 0.7251960054 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3538736571 |
| GSE13712_SHEAR | Down | -0.2104517726 |
| GSE13712_STATIC | Down | -0.0941001273 |
| GSE19018 | Down | -0.3760114781 |
| GSE19899_A1 | Down | -0.0359730266 |
| GSE19899_A2 | Down | -0.2334239394 |
| PubMed_21979375_A1 | Down | -0.0825431350 |
| PubMed_21979375_A2 | Down | -0.4068645112 |
| GSE35957 | Down | -0.5315223789 |
| GSE36640 | Down | -0.2228318399 |
| GSE54402 | Up | 0.0191939669 |
| GSE9593 | Up | 0.4353260360 |
| GSE43922 | Down | -0.0383574506 |
| GSE24585 | Up | 0.3305597014 |
| GSE37065 | Up | 0.1761480861 |
| GSE28863_A1 | Down | -0.1048870168 |
| GSE28863_A2 | Down | -0.1199081865 |
| GSE28863_A3 | Up | 0.0842517966 |
| GSE28863_A4 | Up | 0.1188304046 |
| GSE48662 | Down | -0.0134340397 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018083 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
