HCSGD entry for SFTPC
1. General information
| Official gene symbol | SFTPC |
|---|---|
| Entrez ID | 6440 |
| Gene full name | surfactant protein C |
| Other gene symbols | BRICD6 PSP-C SFTP2 SMDP2 SP-C |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005771 | Multivesicular body | IEA | cellular_component |
| GO:0007585 | Respiratory gaseous exchange | IEA | biological_process |
| GO:0007623 | Circadian rhythm | IEA | biological_process |
| GO:0009749 | Response to glucose | IEA | biological_process |
| GO:0032496 | Response to lipopolysaccharide | IEA | biological_process |
| GO:0032526 | Response to retinoic acid | IEA | biological_process |
| GO:0033189 | Response to vitamin A | IEA | biological_process |
| GO:0042803 | Protein homodimerization activity | IEA | molecular_function |
| GO:0051260 | Protein homooligomerization | IEA | biological_process |
| GO:0051384 | Response to glucocorticoid | IEA | biological_process |
| GO:0051591 | Response to cAMP | IEA | biological_process |
| GO:0055093 | Response to hyperoxia | IEA | biological_process |
| GO:0070741 | Response to interleukin-6 | IEA | biological_process |
| GO:0070848 | Response to growth factor | IEA | biological_process |
| GO:0071260 | Cellular response to mechanical stimulus | IEA | biological_process |
| GO:0071732 | Cellular response to nitric oxide | IEA | biological_process |
| GO:0097208 | Alveolar lamellar body | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6941078606 | 0.6789981422 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1096422124 |
| GSE13712_SHEAR | Up | 0.0100249575 |
| GSE13712_STATIC | Down | -0.0128857702 |
| GSE19018 | Up | 0.0105009288 |
| GSE19899_A1 | Down | -0.0444769712 |
| GSE19899_A2 | Up | 0.0785601983 |
| PubMed_21979375_A1 | Down | -0.1858334001 |
| PubMed_21979375_A2 | Down | -0.1493609893 |
| GSE35957 | Down | -0.0388192876 |
| GSE36640 | Up | 0.1771882316 |
| GSE54402 | Down | -0.0872076918 |
| GSE9593 | Up | 0.0328708555 |
| GSE43922 | Up | 0.0257867359 |
| GSE24585 | Up | 0.0830062796 |
| GSE37065 | Up | 0.1385581528 |
| GSE28863_A1 | Down | -0.2198751332 |
| GSE28863_A2 | Down | -0.1271093037 |
| GSE28863_A3 | Up | 0.2955688923 |
| GSE28863_A4 | Up | 0.3527574078 |
| GSE48662 | Up | 0.0202142597 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 23268535 | These four genes encode two surfactant proteins, surfactant protein C (encoded by SFTPC) and surfactant protein A2 (SFTPA2), and two components of the telomerase complex, telomerase reverse transcriptase (TERT) and the RNA component of telomerase (TERC) |
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