HCSGD entry for TNS3


1. General information

Official gene symbolTNS3
Entrez ID64759
Gene full nametensin 3
Other gene symbolsTEM6 TENS1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005925Focal adhesionIEAcellular_component
GO:0008284Positive regulation of cell proliferationIEAbiological_process
GO:0016477Cell migrationIEAbiological_process
GO:0035556Intracellular signal transductionIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048286Lung alveolus developmentIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.09452596790.13170794040.64406368110.6994924738

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0434853827
GSE13712_SHEARUp0.8273007430
GSE13712_STATICUp0.6459101168
GSE19018Down-0.1422047210
GSE19899_A1Down-0.5163646044
GSE19899_A2Down-0.1388764346
PubMed_21979375_A1Down-0.7857224788
PubMed_21979375_A2Down-0.0774724652
GSE35957Up0.1800955410
GSE36640Up0.0680777834
GSE54402Down-0.1798176066
GSE9593Up0.4768258522
GSE43922Down-0.6018882729
GSE24585Up0.0356317902
GSE37065Up0.3621197032
GSE28863_A1Up0.5593963329
GSE28863_A2Up0.5819262913
GSE28863_A3Down-0.0163363543
GSE28863_A4Down-0.5204594887
GSE48662Up0.7696753326

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-375MIMAT0000728MIRT019755MicroarrayFunctional MTI (Weak)20215506
hsa-miR-21-5pMIMAT0000076MIRT030755MicroarrayFunctional MTI (Weak)18591254
hsa-miR-342-3pMIMAT0000753MIRT043688CLASHFunctional MTI (Weak)23622248
hsa-let-7i-5pMIMAT0000415MIRT046548CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.