HCSGD entry for SLC5A5


1. General information

Official gene symbolSLC5A5
Entrez ID6528
Gene full namesolute carrier family 5 (sodium iodide symporter), member 5
Other gene symbolsNIS TDH1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005634NucleusIDAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006590Thyroid hormone generationTASbiological_process
GO:0006810TransportTASbiological_process
GO:0006811Ion transportTASbiological_process
GO:0008507Sodium:iodide symporter activityIEAmolecular_function
GO:0015111Iodide transmembrane transporter activityIMPmolecular_function
GO:0015705Iodide transportIMPbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0034220Ion transmembrane transportIMP TASbiological_process
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:0071320Cellular response to cAMPIEPbiological_process
GO:0071371Cellular response to gonadotropin stimulusIEPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.26029848410.90212051970.95322996241.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0368619604
GSE13712_SHEARUp0.1446073118
GSE13712_STATICDown-0.0535232807
GSE19018Up0.0022024936
GSE19899_A1Up0.0156800888
GSE19899_A2Up0.3577249689
PubMed_21979375_A1Up0.0550084471
PubMed_21979375_A2Down-0.1892794170
GSE35957Up0.3798693522
GSE36640Up0.1355727178
GSE54402Up0.1059220446
GSE9593Down-0.0791973230
GSE43922Up0.0771339529
GSE24585Up0.1862062910
GSE37065Down-0.1603776547
GSE28863_A1Down-0.0114391287
GSE28863_A2Up0.1180776205
GSE28863_A3Up0.3490592890
GSE28863_A4Up0.1877448244
GSE48662Up0.1074616576

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-let-7f-5pMIMAT0000067MIRT032088qRT-PCRNon-Functional MTI (Weak)19956384
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.