HCSGD entry for SLIT1

1. General information

Official gene symbolSLIT1
Entrez ID6585
Gene full nameslit homolog 1 (Drosophila)
Other gene symbolsMEGF4 SLIL1 SLIT-1 SLIT3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005509Calcium ion bindingIEA NASmolecular_function
GO:0005615Extracellular spaceNAScellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0007411Axon guidanceIDA TASbiological_process
GO:0008045Motor neuron axon guidanceIMPbiological_process
GO:0021510Spinal cord developmentIEAbiological_process
GO:0021834Chemorepulsion involved in embryonic olfactory bulb interneuron precursor migrationIDAbiological_process
GO:0031290Retinal ganglion cell axon guidanceIEAbiological_process
GO:0033563Dorsal/ventral axon guidanceIEAbiological_process
GO:0040023Establishment of nucleus localizationIEAbiological_process
GO:0043395Heparan sulfate proteoglycan bindingIEAmolecular_function
GO:0048495Roundabout bindingIPImolecular_function
GO:0048843Negative regulation of axon extension involved in axon guidanceIEAbiological_process
GO:0048846Axon extension involved in axon guidanceIDAbiological_process
GO:0048853Forebrain morphogenesisNASbiological_process
GO:0050919Negative chemotaxisIDAbiological_process
GO:0051964Negative regulation of synapse assemblyISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.79835148740.64611611260.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1390860792
GSE13712_SHEARUp0.0254070315
GSE13712_STATICUp0.0456205660
GSE19018Up0.2162723952
GSE19899_A1Up0.1042108955
GSE19899_A2Up0.0744019918
PubMed_21979375_A1Down-0.2729523559
PubMed_21979375_A2Down-0.1828914772
GSE35957Up0.0884181528
GSE36640Up0.1318336434
GSE54402Up0.0078962920
GSE9593Down-0.1690343679
GSE43922Up0.0858965184
GSE24585Down-0.3968294687
GSE37065Up0.0934096191
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.0144316562

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-421MIMAT0003339MIRT039395CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.