HCSGD entry for SORD


1. General information

Official gene symbolSORD
Entrez ID6652
Gene full namesorbitol dehydrogenase
Other gene symbolsSORD1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003939L-iditol 2-dehydrogenase activityIDA ISSmolecular_function
GO:0005615Extracellular spaceTAScellular_component
GO:0006006Glucose metabolic processTASbiological_process
GO:0006062Sorbitol catabolic processIDAbiological_process
GO:0008270Zinc ion bindingIDA IEA ISSmolecular_function
GO:0016020MembraneIDAcellular_component
GO:0016491Oxidoreductase activityIEAmolecular_function
GO:0030246Carbohydrate bindingNASmolecular_function
GO:0030317Sperm motilityISS NASbiological_process
GO:0031514Motile ciliumISScellular_component
GO:0031966Mitochondrial membraneIEAcellular_component
GO:0046370Fructose biosynthetic processIDAbiological_process
GO:0051160L-xylitol catabolic processIDAbiological_process
GO:0051164L-xylitol metabolic processIDAbiological_process
GO:0051287NAD bindingIDAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.91942953160.04740095740.99999024730.4083929951

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2063380785
GSE13712_SHEARUp0.0447089616
GSE13712_STATICUp0.1652636282
GSE19018Up0.0790543822
GSE19899_A1Down-0.1557148013
GSE19899_A2Down-0.3649311372
PubMed_21979375_A1Up0.0039221526
PubMed_21979375_A2Down-0.4881468203
GSE35957Down-0.6699475369
GSE36640Down-0.2818639119
GSE54402Up0.4004278617
GSE9593Down-0.3483811159
GSE43922Down-0.1205059710
GSE24585Down-0.7721729141
GSE37065Up0.1452119287
GSE28863_A1Down-0.0886834539
GSE28863_A2Down-0.0449009875
GSE28863_A3Up0.1609376296
GSE28863_A4Up0.0666535123
GSE48662Down-0.2266966669

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

NADHDB00157 NUTR00041 | DB01907 | EXPT02287 | DB03527
Cp-166572, 2-Hydroxymethyl-4-(4-N,N-Dimethylaminosulfonyl-1-Piperazino)-PyrimidineDB04478 EXPT00235

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-98-5pMIMAT0000096MIRT027448MicroarrayFunctional MTI (Weak)19088304
hsa-miR-484MIMAT0002174MIRT042343CLASHFunctional MTI (Weak)23622248
hsa-miR-10a-5pMIMAT0000253MIRT047657CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.