HCSGD entry for TACR3

1. General information

Official gene symbolTACR3
Entrez ID6870
Gene full nametachykinin receptor 3
Other gene symbolsHH11 NK-3R NK3R NKR TAC3RL
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004995Tachykinin receptor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007217Tachykinin receptor signaling pathwayTASbiological_process
GO:0007218Neuropeptide signaling pathwayTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007568AgingIEAbiological_process
GO:0010460Positive regulation of heart rateIEAbiological_process
GO:0032355Response to estradiolIEAbiological_process
GO:0032590Dendrite membraneIEAcellular_component
GO:0032809Neuronal cell body membraneIEAcellular_component
GO:0042053Regulation of dopamine metabolic processIEAbiological_process
GO:0042220Response to cocaineIEAbiological_process
GO:0042538Hyperosmotic salinity responseIEAbiological_process
GO:0043278Response to morphineIEAbiological_process
GO:0045777Positive regulation of blood pressureIEAbiological_process
GO:0060259Regulation of feeding behaviorIEAbiological_process
GO:0070474Positive regulation of uterine smooth muscle contractionIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82647745530.58151237410.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0576463907
GSE13712_SHEARDown-0.1630364170
GSE13712_STATICUp0.0407902399
GSE19018Up0.0046667296
GSE19899_A1Up0.0076273528
GSE19899_A2Up0.0039718568
PubMed_21979375_A1Down-0.0729371747
PubMed_21979375_A2Down-0.3656926417
GSE35957Down-0.0228549535
GSE36640Up0.0504493113
GSE54402Up0.0549456283
GSE9593Up0.1041506757
GSE43922Up0.0123298334
GSE24585Up0.1499417029
GSE37065Up0.0761652994
GSE28863_A1Down-0.2335390454
GSE28863_A2Up0.2473138589
GSE28863_A3Down-0.0146535317
GSE28863_A4Up0.1505493980
GSE48662Down-0.0643125138

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

OsanetantDB04872 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017215MicroarrayFunctional MTI (Weak)18185580
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.