HCSGD entry for TAF1

1. General information

Official gene symbolTAF1
Entrez ID6872
Gene full nameTAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
Other gene symbolsBA2R CCG1 CCGS DYT3 DYT3/TAF1 KAT4 N-TAF1 NSCL2 OF P250 TAF2A TAFII250 XDP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000117Regulation of transcription involved in G2/M transition of mitotic cell cycleISSbiological_process
GO:0002039P53 bindingIPImolecular_function
GO:0003713Transcription coactivator activityIDAmolecular_function
GO:0004402Histone acetyltransferase activityIDAmolecular_function
GO:0004674Protein serine/threonine kinase activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005669Transcription factor TFIID complexIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0006352DNA-templated transcription, initiationISSbiological_process
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0006367Transcription initiation from RNA polymerase II promoterTASbiological_process
GO:0006368Transcription elongation from RNA polymerase II promoterTASbiological_process
GO:0006974Cellular response to DNA damage stimulusICbiological_process
GO:0008134Transcription factor bindingIPImolecular_function
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0016573Histone acetylationIDAbiological_process
GO:0017025TBP-class protein bindingIPImolecular_function
GO:0018105Peptidyl-serine phosphorylationIDAbiological_process
GO:0018107Peptidyl-threonine phosphorylationIDAbiological_process
GO:0032436Positive regulation of proteasomal ubiquitin-dependent protein catabolic processIDAbiological_process
GO:0043565Sequence-specific DNA bindingISSmolecular_function
GO:0044212Transcription regulatory region DNA bindingISSmolecular_function
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDA IGIbiological_process
GO:0046777Protein autophosphorylationIDA TASbiological_process
GO:0051123RNA polymerase II transcriptional preinitiation complex assemblyISSbiological_process
GO:0060261Positive regulation of transcription initiation from RNA polymerase II promoterISSbiological_process
GO:0070577Histone acetyl-lysine bindingIDAmolecular_function
GO:0071339MLL1 complexIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82092944040.49748031610.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0612069933
GSE13712_SHEARUp0.0035828383
GSE13712_STATICDown-0.0397201056
GSE19018Up0.0285699940
GSE19899_A1Down-0.0098144893
GSE19899_A2Down-0.3189794413
PubMed_21979375_A1Down-0.1555850314
PubMed_21979375_A2Down-0.2857042114
GSE35957Up0.4779865129
GSE36640Down-0.0525693759
GSE54402Up0.0145450240
GSE9593Down-0.0243402161
GSE43922Down-0.0689950614
GSE24585Up0.0229168037
GSE37065Down-0.0053174143
GSE28863_A1Up0.0187975583
GSE28863_A2Up0.0291216880
GSE28863_A3Up0.1440407538
GSE28863_A4Down-0.1479754412
GSE48662Up0.0753934085

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018059MicroarrayFunctional MTI (Weak)18185580
hsa-miR-7-5pMIMAT0000252MIRT025847MicroarrayFunctional MTI (Weak)17612493
hsa-miR-21-5pMIMAT0000076MIRT030916MicroarrayFunctional MTI (Weak)18591254
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.