| 27173733 | H-2h4 mice develop autoimmune disease with extensive hyperplasia and proliferation of thyroid epithelial cells (TEC H/P) and fibrosis |
| 27173733 | Splenic T cells from donors with severe TEC H/P transfer TEC H/P to SCID recipients |
| 27173733 | Splenic T cells from donors with severe TEC H/P transfer TEC H/P to SCID recipients |
| 27173733 | The goal of this study was to determine what factors control TEC H/P development/progression by examining T cells, markers of apoptosis, senescence and proliferation in thyroids of SCID recipients over time |
| 27173733 | X, indicative of cellular senescence, when TEC H/P progressed and thyrocyte proliferation declined |
| 26974507 | The purpose of this study was to elucidate the feasibility of LOT preparation on the chondrogenic differentiation of a scaffold-free tissue-engineered construct (TEC) derived from synovial mesenchymal stem cells (MSCs), construct whose feasibility for cartilage repair has been demonstrated in previous preclinical and clinical studies |
| 26974507 | In addition, TEC prepared from human synovial MSCs under LOT conditions (5% O2; LOT-TEC) showed superior in vitro chondrogenic differentiation capacity compared to that prepared under the usual 20% O2 (normal oxygen tension [NOT]; NOT-TEC), with elevated glycosaminoglycan production and elevated levels of chondrogenic marker gene expression |
| 24263106 | However, their collaborative role in the regulation of TEC homeostasis during thymic aging is largely unknown |
| 24263106 | Blockade of TEC differentiation via conditional FoxN1 gene knockout accelerated the appearance of this phenotype to early middle age, whereas intrathymic infusion of exogenous FoxN1 cDNA into aged WT mice brought only a modest reduction in the proportion of TAp63(+) TECs, but an increase in DeltaNp63(+) TECs in the partially rejuvenated thymus |
| 24263106 | Thus, TAp63 levels are positively correlated with TEC senescence but inversely correlated with expression of FoxN1 and FoxN1-regulated TEC differentiation |
| 24263106 | Thus, TAp63 levels are positively correlated with TEC senescence but inversely correlated with expression of FoxN1 and FoxN1-regulated TEC differentiation |
| 24263106 | Thereby, the p63-FoxN1 regulatory axis in regulation of postnatal TEC homeostasis has been revealed |
| 16391858 | Increasing evidence indicates that tumor-derived endothelial cells (TEC) possess a distinct and unique phenotype in respect to normal endothelial cells and may be able to acquire resistance to drugs |
| 16391858 | However, few functional studies are available on cultured TEC |
| 16391858 | In the present study, we obtained TEC from human breast carcinomas and, to dispel the possibility of contaminating tumor cells, we established six different clones that we characterized at a functional level |
| 16391858 | In addition, breast TEC, at variance to normal endothelial cells, were able to grow and to organize in the absence of serum in capillary-like structures on Matrigel that persisted up to one week |
| 16391858 | These functional characteristics of breast TEC may be relevant for tumor angiogenesis and may indicate an increased pro-angiogenic activity of endothelial cells within the tumor |
| 16391858 | Moreover, our data suggest that TEC might be more appropriate for screening antiangiogenic drugs than normal endothelial cells |
| 9892847 | Thymulin is a Zn-bound nonapeptide produced by the thymic epithelial cells (TEC) whose secretion is modulated by growth hormone (GH), among others |
| 9892847 | Supernatants from TEC lines also showed GH secretagogue activity |
| 9818729 | Thymulin is a Zn-bound nonapeptide produced by the thymic epithelial cells (TEC) whose secretion is modulated by prolactin (PRL) and thyroid hormones, among other hormones |
| 9818729 | Supernatants from TEC lines also showed PRL and TSH secretagogue activity |
