HCSGD entry for TPT1
1. General information
| Official gene symbol | TPT1 |
|---|---|
| Entrez ID | 7178 |
| Gene full name | tumor protein, translationally-controlled 1 |
| Other gene symbols | HRF TCTP p02 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005509 | Calcium ion binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005615 | Extracellular space | IDA | cellular_component |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA TAS | cellular_component |
| GO:0005771 | Multivesicular body | IDA | cellular_component |
| GO:0006816 | Calcium ion transport | IC | biological_process |
| GO:0006874 | Cellular calcium ion homeostasis | IC | biological_process |
| GO:0008134 | Transcription factor binding | IEA | molecular_function |
| GO:0009615 | Response to virus | IEP | biological_process |
| GO:0019827 | Stem cell maintenance | IEA | biological_process |
| GO:0042981 | Regulation of apoptotic process | NAS | biological_process |
| GO:0043066 | Negative regulation of apoptotic process | TAS | biological_process |
| GO:0045298 | Tubulin complex | IDA | cellular_component |
| GO:1902230 | Negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage | IMP | biological_process |
| GO:2000384 | Negative regulation of ectoderm development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9357787090 | 0.3719320277 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0737463133 |
| GSE13712_SHEAR | Down | -0.0083888294 |
| GSE13712_STATIC | Down | -0.0720877604 |
| GSE19018 | Down | -0.1255362388 |
| GSE19899_A1 | Down | -0.0151753156 |
| GSE19899_A2 | Down | -0.0125793401 |
| PubMed_21979375_A1 | Down | -0.1304764584 |
| PubMed_21979375_A2 | Down | -0.0337756364 |
| GSE35957 | Up | 0.0395573878 |
| GSE36640 | Down | -0.0568117901 |
| GSE54402 | Up | 0.1333174819 |
| GSE9593 | Up | 0.0402675876 |
| GSE43922 | Down | -0.0020880950 |
| GSE24585 | Down | -0.1966801900 |
| GSE37065 | Down | -0.2984120363 |
| GSE28863_A1 | Up | 0.2219104963 |
| GSE28863_A2 | Down | -0.1000008398 |
| GSE28863_A3 | Down | -0.2200137967 |
| GSE28863_A4 | Up | 0.1472030532 |
| GSE48662 | Down | -0.3347168636 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT031462 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-374b-5p | MIMAT0004955 | MIRT036803 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039903 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040607 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-29b-3p | MIMAT0000100 | MIRT048369 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT048923 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052061 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-3200-3p | MIMAT0015085 | MIRT052823 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
