HCSGD entry for C5AR1

1. General information

Official gene symbolC5AR1
Entrez ID728
Gene full namecomplement component 5a receptor 1
Other gene symbolsC5A C5AR C5R1 CD88
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000187Activation of MAPK activityTASbiological_process
GO:0001856Complement component C5a bindingIEAmolecular_function
GO:0004878Complement component C5a receptor activityIDAmolecular_function
GO:0004944C5a anaphylatoxin receptor activityIDAmolecular_function
GO:0004982N-formyl peptide receptor activityIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006915Apoptotic processIEAbiological_process
GO:0006935ChemotaxisTASbiological_process
GO:0006954Inflammatory responseIEAbiological_process
GO:0006955Immune responseTASbiological_process
GO:0006968Cellular defense responseTASbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007202Activation of phospholipase C activityTASbiological_process
GO:0007204Positive regulation of cytosolic calcium ion concentrationIEAbiological_process
GO:0007606Sensory perception of chemical stimulusTASbiological_process
GO:0009986Cell surfaceIEAcellular_component
GO:0016323Basolateral plasma membraneIDAcellular_component
GO:0021534Cell proliferation in hindbrainIEAbiological_process
GO:0030593Neutrophil chemotaxisIEAbiological_process
GO:0031100Organ regenerationIEAbiological_process
GO:0032494Response to peptidoglycanIEAbiological_process
GO:0032496Response to lipopolysaccharideIEAbiological_process
GO:0038178Complement component C5a signaling pathwayIDAbiological_process
GO:0042789MRNA transcription from RNA polymerase II promoterIDAbiological_process
GO:0043524Negative regulation of neuron apoptotic processIEAbiological_process
GO:0045177Apical part of cellIDAcellular_component
GO:0050679Positive regulation of epithelial cell proliferationIDAbiological_process
GO:0050830Defense response to Gram-positive bacteriumIEAbiological_process
GO:0070374Positive regulation of ERK1 and ERK2 cascadeIDAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.10047600780.74259001940.66119707501.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.4001025099
GSE13712_SHEARUp0.4634187216
GSE13712_STATICUp0.3350820322
GSE19018Down-0.0782371427
GSE19899_A1Up0.1010424221
GSE19899_A2Up0.0123428647
PubMed_21979375_A1Up0.0964006591
PubMed_21979375_A2Up0.2361173406
GSE35957Down-0.4771329263
GSE36640Up0.9268639508
GSE54402Down-0.0336234123
GSE9593Up0.1163209858
GSE43922Up0.0255938136
GSE24585Up0.1610863406
GSE37065Down-0.1848722491
GSE28863_A1Down-0.2126107353
GSE28863_A2Down-0.4391258910
GSE28863_A3Up0.2522831430
GSE28863_A4Up0.0801502797
GSE48662Up0.5412272703

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT019124MicroarrayFunctional MTI (Weak)18185580
hsa-miR-26b-5pMIMAT0000083MIRT030190MicroarrayFunctional MTI (Weak)19088304
Entries Per Page
Displaying Page of
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.