HCSGD entry for TUBG1


1. General information

Official gene symbolTUBG1
Entrez ID7283
Gene full nametubulin, gamma 1
Other gene symbolsGCP-1 TUBG TUBGCP1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000086G2/M transition of mitotic cell cycleTASbiological_process
GO:0000212Meiotic spindle organizationISSbiological_process
GO:0000226Microtubule cytoskeleton organizationTASbiological_process
GO:0000242Pericentriolar materialIEAcellular_component
GO:0000278Mitotic cell cycleTASbiological_process
GO:0000794Condensed nuclear chromosomeISScellular_component
GO:0000930Gamma-tubulin complexIEA TAScellular_component
GO:0003924GTPase activityIEAmolecular_function
GO:0005200Structural constituent of cytoskeletonTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005525GTP bindingIEAmolecular_function
GO:0005737CytoplasmIDA ISScellular_component
GO:0005813CentrosomeIDAcellular_component
GO:0005814CentrioleIEAcellular_component
GO:0005827Polar microtubuleIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005874MicrotubuleIEAcellular_component
GO:0005881Cytoplasmic microtubuleIEAcellular_component
GO:0007020Microtubule nucleationIEAbiological_process
GO:0031122Cytoplasmic microtubule organizationIEAbiological_process
GO:0031252Cell leading edgeIEAcellular_component
GO:0031513Nonmotile primary ciliumIEAcellular_component
GO:0036064Ciliary basal bodyIEAcellular_component
GO:0045177Apical part of cellIEAcellular_component
GO:0051258Protein polymerizationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.63967947270.26715542720.99999024730.9890025176

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2359735531
GSE13712_SHEARDown-0.0671086414
GSE13712_STATICDown-0.0931818781
GSE19018Down-0.0319759475
GSE19899_A1Up0.0073931599
GSE19899_A2Up0.0540158874
PubMed_21979375_A1Up0.8532590849
PubMed_21979375_A2Up0.0906670345
GSE35957Down-0.9435510855
GSE36640Down-0.3830378959
GSE54402Up0.3266563604
GSE9593Down-0.5377136138
GSE43922Up0.0337780174
GSE24585Down-0.1400524813
GSE37065Up0.0960239249
GSE28863_A1Down-0.1962839121
GSE28863_A2Up0.0741390878
GSE28863_A3Down-0.1163572258
GSE28863_A4Down-0.0132542867
GSE48662Down-0.2351500819

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

VinblastineDB00570 APRD00708

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1229-3pMIMAT0005584MIRT036349CLASHFunctional MTI (Weak)23622248
hsa-miR-324-3pMIMAT0000762MIRT042839CLASHFunctional MTI (Weak)23622248
hsa-miR-148b-3pMIMAT0000759MIRT043581CLASHFunctional MTI (Weak)23622248
hsa-miR-187-3pMIMAT0000262MIRT047028CLASHFunctional MTI (Weak)23622248
hsa-miR-99a-5pMIMAT0000097MIRT048681CLASHFunctional MTI (Weak)23622248
hsa-miR-26a-5pMIMAT0000082MIRT050164CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.