HCSGD entry for C6
1. General information
| Official gene symbol | C6 |
|---|---|
| Entrez ID | 729 |
| Gene full name | complement component 6 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001701 | In utero embryonic development | IEA | biological_process |
| GO:0001970 | Positive regulation of activation of membrane attack complex | IEA | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005579 | Membrane attack complex | IEA | cellular_component |
| GO:0006956 | Complement activation | TAS | biological_process |
| GO:0006958 | Complement activation, classical pathway | IEA | biological_process |
| GO:0019835 | Cytolysis | IEA | biological_process |
| GO:0030449 | Regulation of complement activation | TAS | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0045766 | Positive regulation of angiogenesis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8696153148 | 0.3371343566 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0934238831 |
| GSE13712_SHEAR | Down | -0.0348949267 |
| GSE13712_STATIC | Up | 0.1931664044 |
| GSE19018 | Down | -0.1979435836 |
| GSE19899_A1 | Down | -0.0057188410 |
| GSE19899_A2 | Up | 0.0390424731 |
| PubMed_21979375_A1 | Up | 0.0937626070 |
| PubMed_21979375_A2 | Down | -0.4042340427 |
| GSE35957 | Up | 0.0272215699 |
| GSE36640 | Up | 0.4479366825 |
| GSE54402 | Down | -0.0540556783 |
| GSE9593 | Down | -1.7148298373 |
| GSE43922 | Up | 0.0174332408 |
| GSE24585 | Down | -0.0084138818 |
| GSE37065 | Down | -0.0192877909 |
| GSE28863_A1 | Up | 0.0020763250 |
| GSE28863_A2 | Up | 0.0466539424 |
| GSE28863_A3 | Up | 0.0181564861 |
| GSE28863_A4 | Up | 0.0486015676 |
| GSE48662 | Down | -0.0666931406 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
