HCSGD entry for UBTF
1. General information
| Official gene symbol | UBTF |
|---|---|
| Entrez ID | 7343 |
| Gene full name | upstream binding transcription factor, RNA polymerase I |
| Other gene symbols | NOR-90 UBF UBF-1 UBF1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000183 | Chromatin silencing at rDNA | IEA | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA IEA ISS | cellular_component |
| GO:0006356 | Regulation of transcription from RNA polymerase I promoter | TAS | biological_process |
| GO:0006360 | Transcription from RNA polymerase I promoter | TAS | biological_process |
| GO:0006361 | Transcription initiation from RNA polymerase I promoter | TAS | biological_process |
| GO:0006362 | Transcription elongation from RNA polymerase I promoter | TAS | biological_process |
| GO:0006363 | Termination of RNA polymerase I transcription | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0045943 | Positive regulation of transcription from RNA polymerase I promoter | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7724605790 | 0.1664742373 | 0.9999902473 | 0.7890918452 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1196500709 |
| GSE13712_SHEAR | Up | 0.1284102229 |
| GSE13712_STATIC | Down | -0.0845191617 |
| GSE19018 | Down | -0.3223145616 |
| GSE19899_A1 | Down | -0.1977827590 |
| GSE19899_A2 | Down | -0.1026850009 |
| PubMed_21979375_A1 | Up | 0.1847019517 |
| PubMed_21979375_A2 | Down | -0.3227863685 |
| GSE35957 | Down | -0.3018591303 |
| GSE36640 | Down | -0.4944190965 |
| GSE54402 | Down | -0.1762327545 |
| GSE9593 | Down | -0.2668368627 |
| GSE43922 | Down | -0.0130479326 |
| GSE24585 | Down | -0.0313120913 |
| GSE37065 | Down | -0.0762235313 |
| GSE28863_A1 | Up | 0.5655311559 |
| GSE28863_A2 | Up | 0.2109414178 |
| GSE28863_A3 | Up | 0.3321509845 |
| GSE28863_A4 | Up | 0.2165663161 |
| GSE48662 | Down | -0.1697720006 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023670 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-760 | MIMAT0004957 | MIRT036787 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040964 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042018 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-328-3p | MIMAT0000752 | MIRT043779 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047647 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-26a-5p | MIMAT0000082 | MIRT050121 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
