HCSGD entry for UQCRC2


1. General information

Official gene symbolUQCRC2
Entrez ID7385
Gene full nameubiquinol-cytochrome c reductase core protein II
Other gene symbolsMC3DN5 QCR2 UQCR2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004222Metalloendopeptidase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005739MitochondrionIDAcellular_component
GO:0005743Mitochondrial inner membraneTAScellular_component
GO:0005750Mitochondrial respiratory chain complex IIIIEAcellular_component
GO:0006119Oxidative phosphorylationTASbiological_process
GO:0006508ProteolysisIEAbiological_process
GO:0009060Aerobic respirationTASbiological_process
GO:0022904Respiratory electron transport chainTASbiological_process
GO:0032403Protein complex bindingIEAmolecular_function
GO:0044237Cellular metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.85372227120.36141655710.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0904722278
GSE13712_SHEARDown-0.1397663181
GSE13712_STATICDown-0.0594931032
GSE19018Up0.0275326880
GSE19899_A1Up0.0222758881
GSE19899_A2Down-0.0802124866
PubMed_21979375_A1Down-0.2469303885
PubMed_21979375_A2Up0.2698782330
GSE35957Down-0.1880672956
GSE36640Up0.1018264472
GSE54402Up0.0421887709
GSE9593Down-0.2607278434
GSE43922Down-0.3280628485
GSE24585Down-0.1066126031
GSE37065Down-0.0848522512
GSE28863_A1Up0.2208481865
GSE28863_A2Up0.1884257323
GSE28863_A3Down-0.5049370552
GSE28863_A4Up0.1824122100
GSE48662Down-0.2102615078

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-TriolDB04141 EXPT00697
5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazoleDB04799 -
METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATEDB07401 -
(5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONEDB07763 -
FAMOXADONEDB07778 -
METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATEDB08330 -
2-NONYL-4-HYDROXYQUINOLINE N-OXIDEDB08453 -
UBIQUINONE-2DB08690 -

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-192-5pMIMAT0000222MIRT026478MicroarrayFunctional MTI (Weak)19074876
hsa-miR-26b-5pMIMAT0000083MIRT029392MicroarrayFunctional MTI (Weak)19088304
hsa-miR-23b-3pMIMAT0000418MIRT046254CLASHFunctional MTI (Weak)23622248
hsa-miR-196a-5pMIMAT0000226MIRT048245CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.