HCSGD entry for VLDLR

1. General information

Official gene symbolVLDLR
Entrez ID7436
Gene full namevery low density lipoprotein receptor
Other gene symbolsCARMQ1 CHRMQ1 VLDLRCH
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterISSbiological_process
GO:0001948Glycoprotein bindingIPImolecular_function
GO:0005041Low-density lipoprotein receptor activityTASmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005905Coated pitIEAcellular_component
GO:0006869Lipid transportIEAbiological_process
GO:0006898Receptor-mediated endocytosisIDAbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007399Nervous system developmentTASbiological_process
GO:0007613MemoryTASbiological_process
GO:0008203Cholesterol metabolic processIEAbiological_process
GO:0016020MembraneIDAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0021517Ventral spinal cord developmentIEAbiological_process
GO:0030229Very-low-density lipoprotein particle receptor activityIDAmolecular_function
GO:0034185Apolipoprotein bindingIDA ISSmolecular_function
GO:0034189Very-low-density lipoprotein particle bindingIDAmolecular_function
GO:0034361Very-low-density lipoprotein particleIEAcellular_component
GO:0034436Glycoprotein transportIDAbiological_process
GO:0034437Glycoprotein transporter activityIDAmolecular_function
GO:0034447Very-low-density lipoprotein particle clearanceIDAbiological_process
GO:0038025Reelin receptor activityISSmolecular_function
GO:0038026Reelin-mediated signaling pathwayISSbiological_process
GO:0043235Receptor complexIDAcellular_component
GO:0045860Positive regulation of protein kinase activityIEAbiological_process
GO:0048306Calcium-dependent protein bindingIPImolecular_function
GO:1900006Positive regulation of dendrite developmentISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.28798277420.00164965240.98678430910.0782951439

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-1.3616403891
GSE13712_SHEARDown-1.1901270682
GSE13712_STATICDown-1.6023079341
GSE19018Up1.8832707028
GSE19899_A1Down-0.9185723894
GSE19899_A2Down-1.5413878338
PubMed_21979375_A1Up0.6372187653
PubMed_21979375_A2Down-1.1067067415
GSE35957Down-0.5143987614
GSE36640Down-1.2949719785
GSE54402Down-0.6503196609
GSE9593Up0.1515336531
GSE43922Down-0.0108848877
GSE24585Down-0.3584712073
GSE37065Down-0.2016884378
GSE28863_A1Up0.5488104002
GSE28863_A2Up0.5016484571
GSE28863_A3Down-0.4219932534
GSE28863_A4Down-0.3151257659
GSE48662Up0.2338826477

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018291MicroarrayFunctional MTI (Weak)18185580
hsa-miR-130b-3pMIMAT0000691MIRT020261SequencingFunctional MTI (Weak)20371350
hsa-miR-93-5pMIMAT0000093MIRT028137SequencingFunctional MTI (Weak)20371350
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.