HCSGD entry for ZP2
1. General information
| Official gene symbol | ZP2 |
|---|---|
| Entrez ID | 7783 |
| Gene full name | zona pellucida glycoprotein 2 (sperm receptor) |
| Other gene symbols | ZPA Zp-2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005576 | Extracellular region | IEA TAS | cellular_component |
| GO:0005578 | Proteinaceous extracellular matrix | IEA | cellular_component |
| GO:0005771 | Multivesicular body | ISS | cellular_component |
| GO:0005783 | Endoplasmic reticulum | ISS | cellular_component |
| GO:0005794 | Golgi apparatus | ISS | cellular_component |
| GO:0005886 | Plasma membrane | ISS | cellular_component |
| GO:0006828 | Manganese ion transport | ISS | biological_process |
| GO:0006886 | Intracellular protein transport | ISS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007338 | Single fertilization | TAS | biological_process |
| GO:0007339 | Binding of sperm to zona pellucida | ISS TAS | biological_process |
| GO:0015026 | Coreceptor activity | TAS | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030141 | Secretory granule | ISS | cellular_component |
| GO:0031012 | Extracellular matrix | ISS | cellular_component |
| GO:0032190 | Acrosin binding | IPI | molecular_function |
| GO:0032504 | Multicellular organism reproduction | TAS | biological_process |
| GO:0060046 | Regulation of acrosome reaction | IDA | biological_process |
| GO:0060468 | Prevention of polyspermy | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6660572509 | 0.8398025075 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0317516057 |
| GSE13712_SHEAR | Up | 0.1624979824 |
| GSE13712_STATIC | Down | -0.0938513731 |
| GSE19018 | Up | 0.0493126451 |
| GSE19899_A1 | Up | 0.1481733950 |
| GSE19899_A2 | Up | 0.0305285972 |
| PubMed_21979375_A1 | Up | 0.0002853085 |
| PubMed_21979375_A2 | Down | -0.0333896294 |
| GSE35957 | Up | 0.2091510998 |
| GSE36640 | Up | 0.1090403495 |
| GSE54402 | Down | -0.0298520089 |
| GSE9593 | Down | -0.1398586239 |
| GSE43922 | Up | 0.0255133525 |
| GSE24585 | Down | -0.0929988739 |
| GSE37065 | Down | -0.0501819757 |
| GSE28863_A1 | Up | 0.0503148910 |
| GSE28863_A2 | Up | 0.0520375917 |
| GSE28863_A3 | Up | 0.1882579693 |
| GSE28863_A4 | Up | 0.0443770393 |
| GSE48662 | Down | -0.0540668671 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
