HCSGD entry for FZD5

1. General information

Official gene symbolFZD5
Entrez ID7855
Gene full namefrizzled family receptor 5
Other gene symbolsC2orf31 HFZ5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneIEAcellular_component
GO:0000578Embryonic axis specificationIDAbiological_process
GO:0001525AngiogenesisIBAbiological_process
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIBAcellular_component
GO:0005769Early endosomeIEAcellular_component
GO:0005886Plasma membraneIBA TAScellular_component
GO:0006915Apoptotic processIBAbiological_process
GO:0007409AxonogenesisIBAbiological_process
GO:0007420Brain developmentIBAbiological_process
GO:0008285Negative regulation of cell proliferationIEAbiological_process
GO:0008406Gonad developmentIBAbiological_process
GO:0008595Anterior/posterior axis specification, embryoIDAbiological_process
GO:0009986Cell surfaceIDAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0017147Wnt-protein bindingIPImolecular_function
GO:0019901Protein kinase bindingIPImolecular_function
GO:0030165PDZ domain bindingIBAmolecular_function
GO:0030182Neuron differentiationISSbiological_process
GO:0031076Embryonic camera-type eye developmentIBAbiological_process
GO:0031077Post-embryonic camera-type eye developmentIBAbiological_process
GO:0031625Ubiquitin protein ligase bindingIPImolecular_function
GO:0032729Positive regulation of interferon-gamma productionIMPbiological_process
GO:0033077T cell differentiation in thymusIBAbiological_process
GO:0042813Wnt-activated receptor activityIBA ICmolecular_function
GO:0042995Cell projectionIBAcellular_component
GO:0043507Positive regulation of JUN kinase activityIEAbiological_process
GO:0044332Wnt signaling pathway involved in dorsal/ventral axis specificationIDAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDA IGIbiological_process
GO:0048469Cell maturationIEAbiological_process
GO:0048471Perinuclear region of cytoplasmIEAcellular_component
GO:0060061Spemann organizer formationIDAbiological_process
GO:0060070Canonical Wnt signaling pathwayIDA IMPbiological_process
GO:0060561Apoptotic process involved in morphogenesisIEAbiological_process
GO:0060716Labyrinthine layer blood vessel developmentIBAbiological_process
GO:0071219Cellular response to molecule of bacterial originIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.49167036590.28739743550.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0012712483
GSE13712_SHEARDown-0.0392360913
GSE13712_STATICUp0.1740230891
GSE19018Down-0.0955869792
GSE19899_A1Up0.0193408522
GSE19899_A2Down-0.3199954212
PubMed_21979375_A1Down-0.0484704022
PubMed_21979375_A2Down-0.2177424873
GSE35957Down-0.4993600606
GSE36640Down-0.1070829584
GSE54402Down-0.0544621522
GSE9593Down-0.2889761711
GSE43922Down-0.1747158232
GSE24585Up0.1394822719
GSE37065Up0.1204143904
GSE28863_A1Up0.0450934248
GSE28863_A2Up0.9335765552
GSE28863_A3Up0.2626095915
GSE28863_A4Down-0.0499536626
GSE48662Down-0.2950630311

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT030330MicroarrayFunctional MTI (Weak)19088304
hsa-miR-24-3pMIMAT0000080MIRT030625SequencingFunctional MTI (Weak)20371350
hsa-miR-149-5pMIMAT0000450MIRT045455CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.