HCSGD entry for BIRC7


1. General information

Official gene symbolBIRC7
Entrez ID79444
Gene full namebaculoviral IAP repeat containing 7
Other gene symbolsKIAP LIVIN ML-IAP MLIAP RNF50
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004842Ubiquitin-protein ligase activityIDAmolecular_function
GO:0004869Cysteine-type endopeptidase inhibitor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005794Golgi apparatusIDAcellular_component
GO:0006309Apoptotic DNA fragmentationNASbiological_process
GO:0007257Activation of JUN kinase activityNASbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0010951Negative regulation of endopeptidase activityTASbiological_process
GO:0016567Protein ubiquitinationIDAbiological_process
GO:0019899Enzyme bindingNASmolecular_function
GO:0042127Regulation of cell proliferationIDAbiological_process
GO:0043066Negative regulation of apoptotic processIMP NASbiological_process
GO:0052548Regulation of endopeptidase activityTASbiological_process
GO:0070247Regulation of natural killer cell apoptotic processIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.45734833400.60808184720.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0640200469
GSE13712_SHEARDown-0.0105318683
GSE13712_STATICDown-0.0631732463
GSE19018Up0.1854754437
GSE19899_A1Up0.0481826639
GSE19899_A2Up0.1774130918
PubMed_21979375_A1Down-0.1154075181
PubMed_21979375_A2Down-0.0873818166
GSE35957Down-0.0992336353
GSE36640Up0.0328114182
GSE54402Up0.0387206014
GSE9593Down-0.2007642985
GSE43922Up0.0513757850
GSE24585Down-0.1038544088
GSE37065Down-0.0271118470
GSE28863_A1Down-0.1103126691
GSE28863_A2Down-0.1416385516
GSE28863_A3Up0.4607435203
GSE28863_A4Up0.0987914593
GSE48662Up0.3898554687

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.