HCSGD entry for MCPH1
1. General information
| Official gene symbol | MCPH1 |
|---|---|
| Entrez ID | 79648 |
| Gene full name | microcephalin 1 |
| Other gene symbols | BRIT1 MCT |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005815 | Microtubule organizing center | IEA | cellular_component |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9397295809 | 0.1215822803 | 0.9999902473 | 0.6700246028 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0246349713 |
| GSE13712_SHEAR | Down | -0.0201858319 |
| GSE13712_STATIC | Up | 0.0615491372 |
| GSE19018 | Down | -0.2640946043 |
| GSE19899_A1 | Down | -0.2133955608 |
| GSE19899_A2 | Down | -0.1238415577 |
| PubMed_21979375_A1 | Down | -0.2579366469 |
| PubMed_21979375_A2 | Down | -0.0439552213 |
| GSE35957 | Down | -0.1006540680 |
| GSE36640 | Down | -0.7038258064 |
| GSE54402 | Down | -0.1124849625 |
| GSE9593 | Down | -0.2964939171 |
| GSE43922 | Up | 0.1120771891 |
| GSE24585 | Up | 0.0016166624 |
| GSE37065 | Up | 0.2759242423 |
| GSE28863_A1 | Up | 0.0385183930 |
| GSE28863_A2 | Down | -0.2696940698 |
| GSE28863_A3 | Down | -0.1206413585 |
| GSE28863_A4 | Down | -0.2122613669 |
| GSE48662 | - | - |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017612 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046507 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047634 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-146a-5p | MIMAT0000449 | NA | hsa-miR-146a | 19944095 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
