HCSGD entry for ULBP1
1. General information
| Official gene symbol | ULBP1 |
|---|---|
| Entrez ID | 80329 |
| Gene full name | UL16 binding protein 1 |
| Other gene symbols | RAET1I |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003823 | Antigen binding | IBA | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0019882 | Antigen processing and presentation | IBA | biological_process |
| GO:0030101 | Natural killer cell activation | IDA | biological_process |
| GO:0042267 | Natural killer cell mediated cytotoxicity | IDA | biological_process |
| GO:0046658 | Anchored component of plasma membrane | IDA | cellular_component |
| GO:0046703 | Natural killer cell lectin-like receptor binding | IDA | molecular_function |
| GO:0050776 | Regulation of immune response | TAS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0099757494 | 0.8986927092 | 0.2544407946 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0795962016 |
| GSE13712_SHEAR | Up | 0.1779707844 |
| GSE13712_STATIC | Down | -0.3208763445 |
| GSE19018 | Up | 0.1223324487 |
| GSE19899_A1 | Up | 0.2761086423 |
| GSE19899_A2 | Up | 0.5341636480 |
| PubMed_21979375_A1 | Up | 1.5885850717 |
| PubMed_21979375_A2 | Up | 0.3559794556 |
| GSE35957 | Down | -0.1845230972 |
| GSE36640 | Up | 0.6549579951 |
| GSE54402 | Up | 0.5350532554 |
| GSE9593 | Down | -0.0112696818 |
| GSE43922 | Up | 2.1585056387 |
| GSE24585 | Up | 0.4448210351 |
| GSE37065 | Down | -0.4250265294 |
| GSE28863_A1 | Down | -0.4335152307 |
| GSE28863_A2 | Up | 0.2854044792 |
| GSE28863_A3 | Up | 0.5659048142 |
| GSE28863_A4 | Down | -0.2234412653 |
| GSE48662 | Up | 0.1163266477 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 21764762 | Human NK cells are alerted to induction of p53 in cancer cells by upregulation of the NKG2D ligands ULBP1 and ULBP2 |
| 21764762 | Natural killer (NK) cells are immune cells sensing and eliminating foreign, stressed, transformed, and senescent cells through specialized surface receptors, such as NKG2D, that interacts with several virus- or stress-inducible ligands, including ULBP1 and -2, which are expressed on target cell surfaces |
| 21764762 | In this study, we report that induction of wild-type p53, but not mutant p53, strongly upregulated mRNA and cell surface expression of ULBP1 and -2, whereas expression of other NK cell ligands was not affected |
Entries Per Page
Displaying Page of
