HCSGD entry for RND2
1. General information
| Official gene symbol | RND2 |
|---|---|
| Entrez ID | 8153 |
| Gene full name | Rho family GTPase 2 |
| Other gene symbols | ARHN RHO7 RhoN |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002080 | Acrosomal membrane | IEA | cellular_component |
| GO:0003924 | GTPase activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005769 | Early endosome | IEA | cellular_component |
| GO:0006184 | GTP catabolic process | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | IEA | biological_process |
| GO:0008152 | Metabolic process | TAS | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0047485 | Protein N-terminus binding | IEA | molecular_function |
| GO:0048672 | Positive regulation of collateral sprouting | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9431337677 | 0.2073238593 | 0.9999902473 | 0.8828622068 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0302719641 |
| GSE13712_SHEAR | Down | -0.1299127992 |
| GSE13712_STATIC | Down | -0.0202175799 |
| GSE19018 | Up | 0.1185593035 |
| GSE19899_A1 | Down | -0.0317840165 |
| GSE19899_A2 | Up | 0.3139002679 |
| PubMed_21979375_A1 | Down | -0.5024052213 |
| PubMed_21979375_A2 | Down | -0.3283370038 |
| GSE35957 | Down | -0.0733766929 |
| GSE36640 | Down | -0.3200296088 |
| GSE54402 | Down | -0.3266912334 |
| GSE9593 | Down | -0.0319060205 |
| GSE43922 | Down | -0.3118410021 |
| GSE24585 | Down | -0.1771372997 |
| GSE37065 | Down | -0.0048032303 |
| GSE28863_A1 | Up | 0.0235143061 |
| GSE28863_A2 | Up | 0.0276458468 |
| GSE28863_A3 | Up | 0.1390586036 |
| GSE28863_A4 | Up | 0.0852090783 |
| GSE48662 | Down | -0.0586030568 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-15b-3p | MIMAT0004586 | MIRT038658 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-26a-5p | MIMAT0000082 | MIRT050163 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
