HCSGD entry for TRIM56


1. General information

Official gene symbolTRIM56
Entrez ID81844
Gene full nametripartite motif containing 56
Other gene symbolsRNF109
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004842Ubiquitin-protein ligase activityISS TASmolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005737CytoplasmISScellular_component
GO:0005829CytosolTAScellular_component
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0032479Regulation of type I interferon productionTASbiological_process
GO:0032481Positive regulation of type I interferon productionTASbiological_process
GO:0032608Interferon-beta productionISSbiological_process
GO:0034340Response to type I interferonISSbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0051607Defense response to virusISSbiological_process
GO:0070534Protein K63-linked ubiquitinationISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.12298655830.69496409330.71728987371.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0595113251
GSE13712_SHEARUp0.7149205633
GSE13712_STATICUp0.3917783619
GSE19018Down-0.2283366067
GSE19899_A1Down-0.1810947229
GSE19899_A2Down-0.4421728683
PubMed_21979375_A1Down-0.0538810358
PubMed_21979375_A2Down-0.3899457760
GSE35957Down-0.2685249453
GSE36640Up0.0591780729
GSE54402Up0.3890404506
GSE9593Down-0.0610832992
GSE43922Up0.0496320003
GSE24585Up0.3499381177
GSE37065Up0.1639967202
GSE28863_A1Up0.2310679769
GSE28863_A2Up0.6794116392
GSE28863_A3Up0.2814275427
GSE28863_A4Down-0.0803523511
GSE48662Up0.1500391876

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.