HCSGD entry for USP9X
1. General information
| Official gene symbol | USP9X |
|---|---|
| Entrez ID | 8239 |
| Gene full name | ubiquitin specific peptidase 9, X-linked |
| Other gene symbols | DFFRX FAF FAM |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0004197 | Cysteine-type endopeptidase activity | TAS | molecular_function |
| GO:0004221 | Ubiquitin thiolesterase activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006351 | Transcription, DNA-templated | TAS | biological_process |
| GO:0006367 | Transcription initiation from RNA polymerase II promoter | TAS | biological_process |
| GO:0006511 | Ubiquitin-dependent protein catabolic process | IEA | biological_process |
| GO:0007059 | Chromosome segregation | IEA | biological_process |
| GO:0007067 | Mitosis | IEA | biological_process |
| GO:0007179 | Transforming growth factor beta receptor signaling pathway | IMP TAS | biological_process |
| GO:0007292 | Female gamete generation | TAS | biological_process |
| GO:0008234 | Cysteine-type peptidase activity | TAS | molecular_function |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016579 | Protein deubiquitination | IDA | biological_process |
| GO:0030509 | BMP signaling pathway | IDA | biological_process |
| GO:0045177 | Apical part of cell | IEA | cellular_component |
| GO:0070410 | Co-SMAD binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4412121006 | 0.2283098173 | 0.9999902473 | 0.9199851041 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4834568934 |
| GSE13712_SHEAR | Down | -0.2432061566 |
| GSE13712_STATIC | Down | -0.1567100005 |
| GSE19018 | Up | 0.3805867568 |
| GSE19899_A1 | Down | -0.3596165155 |
| GSE19899_A2 | Down | -0.0908789963 |
| PubMed_21979375_A1 | Down | -0.4131056272 |
| PubMed_21979375_A2 | Up | 0.2576844116 |
| GSE35957 | Up | 0.7814282333 |
| GSE36640 | Up | 0.1897939884 |
| GSE54402 | Down | -0.2204201209 |
| GSE9593 | Up | 0.3221266290 |
| GSE43922 | Down | -0.1887664555 |
| GSE24585 | Down | -0.2411839576 |
| GSE37065 | Down | -0.0850561921 |
| GSE28863_A1 | Down | -0.0295550113 |
| GSE28863_A2 | Up | 0.3980164941 |
| GSE28863_A3 | Up | 0.1155546786 |
| GSE28863_A4 | Up | 0.0575498950 |
| GSE48662 | Up | 0.1171403034 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT031499 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-1180-3p | MIMAT0005825 | MIRT035926 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-330-3p | MIMAT0000751 | MIRT043839 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT045086 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046739 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT048997 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
