HCSGD entry for HIST3H3
1. General information
| Official gene symbol | HIST3H3 |
|---|---|
| Entrez ID | 8290 |
| Gene full name | histone cluster 3, H3 |
| Other gene symbols | H3.4 H3/g H3FT H3t |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000723 | Telomere maintenance | TAS | biological_process |
| GO:0000786 | Nucleosome | IEA | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0006334 | Nucleosome assembly | IEA | biological_process |
| GO:0046982 | Protein heterodimerization activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9065859200 | 0.1800583526 | 0.9999902473 | 0.8216926157 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0945969644 |
| GSE13712_SHEAR | Down | -0.1337070275 |
| GSE13712_STATIC | Up | 0.1897845323 |
| GSE19018 | Up | 0.1729140944 |
| GSE19899_A1 | Down | -0.1278906519 |
| GSE19899_A2 | Up | 0.0512106636 |
| PubMed_21979375_A1 | Up | 0.2770716479 |
| PubMed_21979375_A2 | Down | -0.1728147094 |
| GSE35957 | Down | -0.1509086691 |
| GSE36640 | Down | -0.3870972576 |
| GSE54402 | Down | -0.0585441227 |
| GSE9593 | Down | -0.0505689867 |
| GSE43922 | Up | 0.0348162981 |
| GSE24585 | Up | 0.0948460393 |
| GSE37065 | Down | -0.0990264483 |
| GSE28863_A1 | Down | -0.3842789943 |
| GSE28863_A2 | Down | -0.0236842481 |
| GSE28863_A3 | Down | -0.0333863598 |
| GSE28863_A4 | Down | -0.1310716390 |
| GSE48662 | Down | -0.1872954249 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT024009 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025216 | Proteomics | Functional MTI (Weak) | 21566225 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
